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Dietary fiber compound botanical medicine for treating obesity and hyperlipidemia and preparation method thereof

A technology for dietary fiber and hyperlipidemia, applied in the field of drug development and biological fermentation, can solve the problems of different therapeutic effects, slow onset of therapeutic drugs, and incomplete treatment.

Inactive Publication Date: 2020-01-17
GUOZHONGXINGHE BIOMEDICINE TECH CO LTD +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there are few drugs for the treatment of obesity clinically, and the existing chemotherapy drugs only aim at reducing fat levels and reducing fat absorption, which are not comprehensive in clinical use, and the treatment effect is not good
Although domestic compound preparations of traditional Chinese medicine also play a certain role in the treatment of obesity and hyperlipidemia, the onset of these therapeutic drugs is slow, and the therapeutic effect often varies from person to person, and the therapeutic effect is not exact

Method used

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  • Dietary fiber compound botanical medicine for treating obesity and hyperlipidemia and preparation method thereof
  • Dietary fiber compound botanical medicine for treating obesity and hyperlipidemia and preparation method thereof
  • Dietary fiber compound botanical medicine for treating obesity and hyperlipidemia and preparation method thereof

Examples

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Effect test

Embodiment 1

[0051] In parts by weight, the dietary fiber compound herbal medicine for treating obesity and hyperlipidemia in the present embodiment includes: 15 parts of wax gourd powder, 20 parts of buckwheat flour, 10 parts of lotus leaf, 6 parts of chia seed oil, 5 parts of angelica, 1 part of Chuanxiong, 8 parts of barley, 8 parts of celery seed powder, 12 parts of konjac glucomannan, 3 parts of cassia, 4 parts of salvia miltiorrhiza, 5 parts of soluble starch, 5 parts of onion extract, 8 parts of hawthorn, 0.5 parts of Polygonum multiflorum share.

[0052] Further, the preparation method of the konjac glucomannan comprises the following steps:

[0053] S11, remove the main buds and root fibers of konjac, soak konjac in a sodium chloride solution with a mass fraction of 0.1-0.5% (preferably 0.3%) for 2-3h, clean, peel, freeze-dry and pulverize to obtain konjac flour;

[0054] S12. Inoculate Aspergillus niger species and cellulophagy on independent potato dextrose agar medium respect...

Embodiment 4

[0093] This embodiment also provides a preparation method of the dietary fiber compound herbal medicine for treating obesity and hyperlipidemia described in one of the embodiments 1-3, which includes the following steps:

[0094] S100. Prepare the konjac glucomannan and chia seed oil according to the preparation method described in one of the above-mentioned embodiments 1-3;

[0095] S200. Fully mix the raw materials in one of the parts by weight of Examples 1-3 to obtain a raw material mixture, then place the raw material mixture in a fermenter, add 5-10 times the weight of the raw material mixture (preferably 9 times) deionized water and 0.15-0.25 times (preferably 0.2 times) cellulase and 0.3-0.4 times (preferably 0.35 times) pectinase of the raw material mixture weight, adjust the pH to 6.5-7, And adjust to 35-45°C (preferably 30°C) for fermentation, and separate the liquid fermentation broth after 36-48h (preferably 42h) of fermentation;

[0096] S300. Under the conditio...

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Abstract

The invention discloses a dietary fiber compound botanical medicine for treating obesity and hyperlipidemia and a preparation method thereof. The dietary fiber compound botanical medicine includes (byweight): 10-15 parts of white gourd powder, 10-20 parts of buckwheat flour, 5-10 parts of lotus leaf, 4-6 parts of chia seed oil, 3-5 parts of Chinese angelica, 0.5-1 part of Ligusticum wallichii, 5-8 parts of coix seed, 5-8 parts of celery seed flour, 10-12 parts of konjac glucomannan, 2-3 parts of cassia occidentalis, 3-4 parts of the root of red-rooted salvia, 3-5 parts of soluble starch, 3-5parts of an onion extract, 5-8 parts of hawthorn, and 0.3-0.5 part of polygonum multiflorum. By using a special process to prepare konjac refined flour and chia seed oil, the contents of starch and plant fibers in konjac refined flour are reduced, browning is avoided, and the content of unsaturated fatty acids in chia seed oil is increased. On this basis, through combination of konjac refined flour and chia seed oil and other components rich in dietary fiber according to a reasonable ratio, the effect of effectively lowering glucose and lipids and preventing obesity is achieved.

Description

technical field [0001] The invention relates to the fields of drug development and biological fermentation. More specifically, the present invention relates to a dietary fiber compound herbal medicine for treating obesity and hyperlipidemia and a preparation method thereof. Background technique [0002] Due to factors such as the improvement of living standards, changes in dietary structure (increased intake of saturated fat and reduced intake of complex carbohydrates and crude fiber, etc.), decline in physical labor (decreased activity), and other factors, in recent years, the number of men and women in my country has increased. Blood total cholesterol and LDL levels are higher than before, causing a significant increase in the risk of coronary heart disease. [0003] These hyperlipidemia groups often develop nutritional obesity accompanied by hyperlipidemia, and obesity can cause a variety of chronic diseases, leading to a series of complications or related diseases, espec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61P3/06A61P3/04A61K31/736
CPCA61K31/736A61K36/21A61K36/23A61K36/232A61K36/236A61K36/42A61K36/482A61K36/537A61K36/62A61K36/70A61K36/704A61K36/734A61K36/8962A61K36/8994A61K2236/19A61K2236/331A61K2236/53A61K2236/55A61P3/04A61P3/06A61K2300/00
Inventor 何静仁李玉保
Owner GUOZHONGXINGHE BIOMEDICINE TECH CO LTD
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