Method for preparing medical porous tantalum implant material

A technology of porous tantalum and tantalum powder, applied in medical science, prosthesis, etc., can solve problems affecting the processing of porous tantalum materials, mechanical properties such as insufficient ductility, etc.

Active Publication Date: 2012-11-28
CHONGQING RUNZE PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, porous tantalum, which is used as a medical implant material such as dense bone tissue such as teeth, has obvious deficiencies in the mechanical properties of the material, such as ductility, and will affect the subsequent processing of the porous tantalum material itself, such as molding parts. cutting etc.

Method used

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  • Method for preparing medical porous tantalum implant material
  • Method for preparing medical porous tantalum implant material
  • Method for preparing medical porous tantalum implant material

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Example 1: Weigh 12.2 g of polyvinyl alcohol and put it into a container with 240 ml of distilled water; place it on an electric stove to heat and stir to make it into an aqueous solution of polyvinyl alcohol. Use a 200g balance to weigh 60g of tantalum powder with an average particle size of less than 43 microns and an oxygen content of less than 0.1%, add 50ml of cooled polyvinyl alcohol aqueous solution, stir and mix evenly, and make it into a tantalum powder slurry. Use 10×10×30mm porous polyurethane foam (average pore diameter is 0.48mm, density 0.025g / cm 3 , hardness 50°), the tantalum powder slurry was poured into it by vibrating pressure at 55 times / min and 0.1Mpa. Dry in a vacuum drying oven at a drying temperature of 60° C., a drying time of 8 hours, and a vacuum degree of 1 Pa. Degreasing treatment: the vacuum degree is lower than 10 -4 Pa, temperature 600°C, holding time 120 minutes. Vacuum sintering: vacuum degree is 10 -3 Pa, heat up to 1800°C at 13°C / ...

Embodiment 2

[0025] Example 2: Weigh 10 g of polyvinyl alcohol and put it into a container with 200 ml of distilled water; place it on an electric stove to heat and stir to make it into an aqueous solution of polyvinyl alcohol. Use a 200g balance to weigh 40g of tantalum powder with an average particle size of less than 43 microns and an oxygen content of less than 0.1%, add 32ml of polyvinyl alcohol aqueous solution, stir and mix evenly, and make it into a tantalum powder slurry. Use 10×10×25mm porous polyurethane foam (average pore diameter is 0.56mm, density 0.030g / cm 3 , hardness 60°), the tantalum powder slurry was poured into it by vibrating pressure at 60 times / min and 0.08Mpa. Dry in a vacuum drying oven at a drying temperature of 100°C for a drying time of 4 hours and maintain a vacuum of 10 -2 Pa. Degreasing treatment: vacuum degree 10 -4 Pa, temperature 800°C, holding time 120 minutes. Vacuum sintering: vacuum degree is 10 -4 Pa, heat up to 1600°C at 10°C / min, hold for 180m...

Embodiment 3

[0027] Example 3: Weigh 11 g of polyvinyl alcohol and put it into a container with 220 ml of distilled water; place it on an electric stove to heat and stir to make it into an aqueous solution of polyvinyl alcohol. Use a 200g balance to weigh 45g of tantalum powder with an average particle size of less than 43 microns and an oxygen content of less than 0.1%, add 36ml of polyvinyl alcohol aqueous solution, stir and mix evenly, and make it into a tantalum powder slurry. Use 8×8×25mm porous polyurethane foam (average pore diameter is 0.70mm, density 0.035g / cm 3 , hardness 70°), the tantalum powder slurry was poured into it by vibrating pressure method at 80 times / min and 0.2Mpa. Dry in a vacuum drying oven at a drying temperature of 80°C for a drying time of 6 hours and maintain a vacuum of 10 -1 Pa. Degreasing treatment: vacuum degree 10 -3 Pa, temperature 700°C, holding time 90 minutes. Vacuum sintering: vacuum degree is 10 -3 Pa, heat up to 1700°C at 20°C / min, hold for 24...

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Abstract

The invention discloses a method for preparing a medical porous tantalum material. The method comprises the following steps of: mixing a poly ethanol aqueous solution and tantalum powder to obtain slurry, wherein the mass concentration of the poly ethanol aqueous solution is 2 to 8 percent; injecting the slurry into an organic foam by vibrating and pressurizing, wherein the vibrating frequency is 20 to 80 times/min; drying; degreasing; sintering, namely raising temperature to 1,500 to 1,800 DEG C at the speed of 10 to 20 DEG C/min under the vacuum degree of 10<-4> to 10<-3>Pa, preserving heat for 120 to 240 minutes, cooling to 200 to 300 DEG C along with a furnace, raising temperature to 1,500 to 1,800 DEG C at the speed of 10 to 20 DEG C/min again, preserving heat for 180 to 240 minutes, raising temperature to 2,000 to 2,200 DEG C at the speed of 5 to 10 DEG C/min, and preserving heat for 120 to 360 minutes; cooling; and performing thermal treatment, namely raising temperature to 800 to 900 DEG C at the speed of 10 to 20 DEG C/min under the vacuum degree of 10<-4> to 10<-3> Pa, preserving heat for 240 to 480 minutes, cooling to 400 DGE C at the speed of 2 to 5 DGE C/min, preserving heat for 120 to 300 minutes, and cooling to room temperature along with the furnace. The porous tantalum prepared by the method is very suitable to be used for the medical implant material for replacing bearing bone tissues, and biocompatibility and the mechanical property can be guaranteed simultaneously.

Description

technical field [0001] The invention relates to a preparation method of a porous medical metal implant material, in particular to a preparation method of a medical porous tantalum implant material suitable for replacing load-bearing bone tissue. Background technique [0002] Porous medical metal implant materials have important and special purposes such as treating bone tissue trauma, femoral tissue necrosis, and replacing dense bone tissue such as teeth. The common materials of this type include porous metal stainless steel and porous metal titanium. As a porous implant material used in the treatment of bone tissue trauma and femoral tissue necrosis, its porosity should reach 30-80%, and the pores should be all connected and evenly distributed, or it should be consistent with the growth of human bone tissue as needed. , and reduce the weight of the material itself, so that it is suitable for human implantation. [0003] As for the refractory metal tantalum, due to its exce...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C22C1/08C22C27/02A61L27/04A61L27/56
CPCB22F3/1137A61L27/04B22F3/24A61L27/56A61L27/047C22C1/08C22C27/02B22F3/1021
Inventor 叶雷
Owner CHONGQING RUNZE PHARM CO LTD
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