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Probiotic composition with effect of relieving hyperuricemia and application thereof

A technology of probiotics and composition, applied in the field of microorganisms, can solve the problems of not being able to exert the synergistic effect of various probiotics, not fully considering the stability of probiotics, and the rapid loss of viable bacteria, so as to increase the diversity of intestinal flora Sex, enhance the intestinal mucosal barrier, enhance the effect of relief

Active Publication Date: 2020-05-26
JIANGSU WECARE BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, it should be pointed out that the above-mentioned single probiotics are used to intervene in high uric acid, and the types of probiotics used are relatively small. In contrast, the number of intestinal flora in the human body is large, and the use of a single probiotic to regulate intestinal flora is limited. And can not play a synergistic effect between a variety of probiotics
In addition, hyperuricemia is accompanied by different side effects, such as bacterial imbalance and increased intestinal wall permeability, etc. The above-mentioned single-strain regimen focuses on the effect of reducing uric acid concentration without in-depth research on the relieving effect of other side effects
Finally, in the process of preparation, the above-mentioned scheme did not fully consider the stability of probiotics during storage, which may easily lead to the rapid loss of the number of viable bacteria, resulting in problems such as weakening of the effect

Method used

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  • Probiotic composition with effect of relieving hyperuricemia and application thereof
  • Probiotic composition with effect of relieving hyperuricemia and application thereof
  • Probiotic composition with effect of relieving hyperuricemia and application thereof

Examples

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Effect test

Embodiment 1

[0039] This embodiment provides a probiotic composition with the effect of relieving high uric acid, the formula is as follows:

[0040]It includes the following components in parts by weight: 30 parts of polydextrose, 20 parts of resistant dextrin, 33 parts of fructooligosaccharide, 4 parts of Lactobacillus gasseri LG08 freeze-dried powder, 6 parts of Bifidobacterium longum BL21 freeze-dried powder, 5 parts of Lactobacillus salivarius LS97 freeze-dried powder, 2 parts of Lactobacillus plantarum Lp90 freeze-dried powder.

[0041] And provide its preparation method, specifically comprise the following steps:

[0042] S1. Preparation of compound probiotic composition: activate Lactobacillus gasseri LG08, Bifidobacterium longum BL21, Lactobacillus salivarius LS97 freeze-dried powder and Lactobacillus plantarum Lp90 in MRS medium test tubes respectively to obtain first-grade seed liquid, and then Transfer the first-class seeds to MRS liquid medium respectively, the culture condit...

Embodiment 2

[0047] This embodiment provides another probiotic composition with the effect of relieving hyperuricemia, the formula is as follows:

[0048] It includes the following components in parts by weight: 50 parts of polydextrose, 10 parts of resistant dextrin, 23 parts of fructooligosaccharide, 8 parts of Lactobacillus gasseri LG08 freeze-dried powder, 2 parts of Bifidobacterium longum BL21 freeze-dried powder, 3 parts of Lactobacillus salivarius LS97 freeze-dried powder, 4 parts of Lactobacillus plantarum Lp90 freeze-dried powder.

[0049] Its preparation method is identical with embodiment 1.

Embodiment 3

[0051] This embodiment provides another probiotic composition with the effect of relieving hyperuricemia, the formula is as follows:

[0052] The following components are included in parts by weight: 40 parts of polydextrose, 15 parts of resistant dextrin, 28 parts of fructooligosaccharide, 6 parts of Lactobacillus gasseri LG08 freeze-dried powder, 4 parts of Bifidobacterium longum BL21 freeze-dried powder, 4 parts of Lactobacillus salivarius LS97 freeze-dried powder, 3 parts of Lactobacillus plantarum Lp90 freeze-dried powder.

[0053] Its preparation method is identical with embodiment 1.

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Abstract

The invention relates to the field of microorganisms, in particular to a probiotic composition with an effect of relieving hyperuricemia and an application of the probiotic composition. The inventiondiscloses a probiotic composition. The composition comprises the following components in parts by weight: 30-50 parts of polydextrose, 10-20 parts of resistant dextrin, 23-33 parts of fructo-oligosaccharide, 4-8 parts of lactobacillus gasseri LG08 freeze-dried powder, 2-6 parts of bifidobacterium longum BL21 freeze-dried powder, 3-5 parts of lactobacillus salivarius LS97 freeze-dried powder and 2-4 parts of lactobacillus plantarum Lp90 freeze-dried powder. Under the condition of the same probiotic intake, the uric acid reducing effect is better than that of a single probiotic, the side reaction caused by the hyperuricemia symptom can be improved, and on the other hand, the stability of the probiotic storage process can be improved.

Description

technical field [0001] The invention relates to the field of microorganisms, in particular to a probiotic composition capable of relieving hyperuricemia and its application. Background technique [0002] With the improvement of people's living standards, the incidence of many chronic diseases is also increasing, such as hyperuricemia. Hyperuricemia is a disease in which blood uric acid exceeds the normal value, in which uric acid is easily precipitated in the form of sodium salt in joints, soft tissues, cartilage and kidneys, causing human organ and tissue lesions, leading to gout and serious complications. According to statistics, there are about 120 million patients with hyperuricemia in my country at present, and traditional treatment methods include drugs, diet restrictions, etc., which have problems such as drug dependence, side effects, and difficulty in diet control. Symptoms approach without delay. [0003] Hundreds of millions of bacteria live in the human gut, mos...

Claims

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Application Information

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IPC IPC(8): A61K35/747A61K47/36A61K47/26A61P19/06A23L33/135A23L33/125A23L2/39A61K35/745
CPCA61K35/747A61K35/745A61K47/36A61K47/26A61P19/06A23L33/135A23L33/125A23L2/39A23V2002/00A23V2400/145A23V2400/181A23V2400/533A23V2400/169A61K2300/00A23V2200/30A23V2200/32A23V2250/5114A23V2250/51A23V2250/28
Inventor 方曙光吴明科王思清刘春朱建国
Owner JIANGSU WECARE BIOTECHNOLOGY CO LTD
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