A non-invasive blood lipid detection device and detection method based on near-infrared spectroscopy

Abstract

The invention discloses a non-invasive blood lipid detection device and detection method based on near-infrared spectroscopy, wherein the detection device includes a broadband light source laser, an optical fiber beam splitter, a first focusing lens, a second focusing lens, a first optical fiber probe, and a second optical fiber probe, the third focusing lens, the fourth focusing lens, the first near-infrared spectrometer, the second near-infrared spectrometer, a lock-in amplifier, a heart rate measuring instrument and a computer; The relative value of the characteristic peak of blood lipid to the characteristic peak of hemoglobin at 2298nm and the known blood lipid content of the human body, a large amount of data fitting to obtain the relationship curve between the relative intensity of the characteristic peak of blood lipid in the near-infrared transmission spectrum and the content of blood lipid, and then detect the real-time blood lipid of the human body content. The invention has many advantages such as real-time detection, rapidity, safety and environmental protection, and has broad application prospects in the fields of biological non-invasive detection and disease prevention and treatment.

Description

technical field [0001] The invention relates to the technical field of biological non-invasive detection, in particular to a near-infrared spectrum-based non-invasive blood lipid detection device and detection method. Background technique [0002] In recent years, with the rapid development of my country's economy, people's living standards have been continuously improved, but due to unreasonable diet and living habits and environmental pollution, the incidence of a series of diseases such as hyperlipidemia has increased significantly. Patients with hyperlipidemia will cause a series of complications due to hyperlipidemia, including a series of serious diseases such as venous sclerosis, coronary heart disease, hypertension, myocardial infarction, cerebral infarction, and brain atrophy. Statistics show that more than 2 million people die from cardiovascular and cerebrovascular diseases in my country every year, accounting for 40% of the number of deaths, ranking first among v...

AI Technical Summary

Problems solved by technology

[0003] The current blood lipid detection technology mainly adopts invasive or minimally invasive methods. For such methods, a large number of chemical reagents are often required for detection, which will pollute the environment and consume a lot of time. The most important thing is that it may cause wound infection. impact on patient safety

At present, most regular hospitals use biochemical detectors for blood lipid detection. Although this method has high precision, it takes a long time and costs a lot, and it is impossible to realize real-time detection of blood lipids.

However, the minimally invasive blood lipid detectors on the market often require patients to take samples by themselves for testing. Although it is more convenient, the accuracy is not high and the reliability is low.

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