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Near-infrared spectrum-based tissue blood flow and blood oxygen imaging device and method

A near-infrared spectroscopy and imaging device technology, applied in the field of biomedical engineering, can solve the problems of long time and high cost

Pending Publication Date: 2020-07-03
BEIJING UNIV OF TECH
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Problems solved by technology

[0004] At present, the combination of the above two technologies is mostly only the integration of the measurement device, at the cost of increasing the number of channels to obtain blood flow and blood oxygen data at multiple locations, which is costly and time-consuming

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  • Near-infrared spectrum-based tissue blood flow and blood oxygen imaging device and method

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[0041] In order to make the object, technical solution and advantages of the present invention clearer, the implementation of the present invention will be further described in detail below in conjunction with specific embodiments and with reference to the accompanying drawings.

[0042] The present invention provides a tissue blood flow blood oxygen imaging device based on near-infrared spectroscopy, figure 1 It shows the system block diagram of the tissue blood flow blood oxygen imaging device based on near-infrared spectrum according to the present invention, and the device includes:

[0043] Long coherent lasers in the near-infrared band (1), (2), (3), the central wavelength of the laser can be selected between 650nm-950nm, the coherence length is greater than 10m, and the power is greater than 50mW. In the embodiments of the present disclosure, the central wavelengths of the lasers are listed as 685 nm, 785 nm and 830 nm, and other wavelengths can be selected according to...

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Abstract

The present invention discloses a near-infrared spectrum-based tissue blood flow and blood oxygen imaging device and method, which can realize detection and imaging of different depths of blood flow and blood oxygen of a tested tissue. The imaging device is characterized in that light sources are coherent lasers with near-infrared wavelengths, the lasers with the multiple wavelengths are coupled to a multi-mode optical fiber, and then laser light is irradiated to the surface of the tested tissue in sequence after being switched by an optical switch; a detector is a single-photon counter, the intensity of scattered light spots generated on the surface of the tissue after irradiation by the light sources is detected by a single-mode optical fiber and is converted into electric pulse signalsto be transmitted to an upper computer, and a multichannel detection optical fiber can realize detection of different positions; the upper computer realizes counting of the electric pulse signals andcalculation of light intensity autocorrelation based on a software correlator, attenuation of the intensity of light with different wavelengths is used for calculating the blood oxygen of the tissue,and meanwhile, the attenuation speed of light intensity autocorrelation is used for calculating the blood flow of the tissue; and detection and imaging of different depths of the blood flow and the blood oxygen can be realized by adjusting position distribution of the light source optical fiber and the detection optical fiber.

Description

technical field [0001] The invention relates to the technical field of biomedical engineering, in particular to a near-infrared spectrum-based tissue blood flow and blood oxygen imaging device and method. Background technique [0002] The blood flow and blood oxygen parameters of biological tissue are important indicators to measure whether the body is normal or not. At the same time, the imaging of tissue blood flow and blood oxygen is of great significance to the diagnosis and treatment of brain diseases, breast cancer and cardiovascular diseases. [0003] Since the main chromophores of biological tissues such as water, hemoglobin and fat have relatively weak absorption in the near-infrared band, the near-infrared spectrum (650nm-950nm) has good penetration into biological tissues, and can realize deep biological tissue hemoglobin (HbO 2 ), deoxygenated hemoglobin (Hb) and blood oxygen saturation (StO 2 ), a technique commonly referred to as near-infrared spectroscopy (NI...

Claims

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Application Information

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IPC IPC(8): A61B5/1455
CPCA61B5/14551A61B5/14552
Inventor 李哲葛奇思冯金超贾克斌
Owner BEIJING UNIV OF TECH
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