Magnetic resonance perfusion-diffusion image registration method for acute ischemic stroke

A technology of ischemic stroke and magnetic resonance, which is applied in medical science, telemetry patient monitoring, sensors, etc., can solve problems such as difficult to solve DWI and ASL precise registration problems, so as to avoid excessive loss of detailed information and avoid artifacts and noise, contributing to stroke diagnosis and prognosis
CN111407277AActive Publication Date: 2020-07-14WUHAN INST OF PHYSICS & MATHEMATICS CHINESE ACADEMY OF SCI
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
WUHAN INST OF PHYSICS & MATHEMATICS CHINESE ACADEMY OF SCI
Publication Date
2020-07-14

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Abstract

The invention discloses a magnetic resonance perfusion-diffusion image registration method for an acute ischemic stroke. The magnetic resonance perfusion-diffusion image registration method comprisesthe steps of firstly, through pretreatment of resampling and the like, keeping a structural image, a functional image and a template space of the stroke consistent in spatial resolution; secondly, registering the structural image of the stroke into the template space and obtaining a deformation vector field; thirdly, mapping the functional image (a cerebral blood flow chart and a diffusion-weighted image) of the stroke into the template space by using the deformation vector field and achieving correspondence of a perfusion image and a diffusion image of the stroke at a spatial anatomical position; and finally, quantitatively analyzing clinical diagnosis and treatment indicators, such as mismatch, size, volume and position of an infarct core / penumbra in a magnetic resonance diffusion-perfusion image of the stroke. Accurate magnetic resonance perfusion-diffusion image registration for the stroke is conducive to effective evaluation of a time window and a tissue window of a patient with the stroke, and the patient is benefited.
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Description

technical field

[0001] The invention belongs to the technical field of magnetic resonance imaging and digital images, and in particular relates to a magnetic resonance perfusion-diffusion image registration method for acute ischemic stroke. Background technique

[0002] Stroke (also known as apoplexy) is a common cerebrovascular disease with an incidence rate of 246.8 / 100,000 and a mortality rate of 114.8 / 100,000, of which ischemic stroke accounts for about 87%, and cerebral hemorrhage accounts for about 10%. Subarachnoid hemorrhage accounts for about 3%, which brings a heavy burden to the society. Acute ischemic stroke, also known as acute cerebral infarction, is a focal brain dysfunction disease caused by interruption of blood supply to local brain tissue, accounting for 69.6% of stroke in my country. Once the onset occurs, the key to treatment and prognosis is to accurately define the period of the disease (time window), rescue the ischemic penumbra (tissue window), stri...

Claims

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