Magnetic resonance perfusion-diffusion image registration method for acute ischemic stroke

Abstract

The invention discloses a magnetic resonance perfusion-diffusion image registration method for an acute ischemic stroke. The magnetic resonance perfusion-diffusion image registration method comprisesthe steps of firstly, through pretreatment of resampling and the like, keeping a structural image, a functional image and a template space of the stroke consistent in spatial resolution; secondly, registering the structural image of the stroke into the template space and obtaining a deformation vector field; thirdly, mapping the functional image (a cerebral blood flow chart and a diffusion-weighted image) of the stroke into the template space by using the deformation vector field and achieving correspondence of a perfusion image and a diffusion image of the stroke at a spatial anatomical position; and finally, quantitatively analyzing clinical diagnosis and treatment indicators, such as mismatch, size, volume and position of an infarct core / penumbra in a magnetic resonance diffusion-perfusion image of the stroke. Accurate magnetic resonance perfusion-diffusion image registration for the stroke is conducive to effective evaluation of a time window and a tissue window of a patient with the stroke, and the patient is benefited.

Description

technical field [0001] The invention belongs to the technical field of magnetic resonance imaging and digital images, and in particular relates to a magnetic resonance perfusion-diffusion image registration method for acute ischemic stroke. Background technique [0002] Stroke (also known as apoplexy) is a common cerebrovascular disease with an incidence rate of 246.8 / 100,000 and a mortality rate of 114.8 / 100,000, of which ischemic stroke accounts for about 87%, and cerebral hemorrhage accounts for about 10%. Subarachnoid hemorrhage accounts for about 3%, which brings a heavy burden to the society. Acute ischemic stroke, also known as acute cerebral infarction, is a focal brain dysfunction disease caused by interruption of blood supply to local brain tissue, accounting for 69.6% of stroke in my country. Once the onset occurs, the key to treatment and prognosis is to accurately define the period of the disease (time window), rescue the ischemic penumbra (tissue window), stri...

AI Technical Summary

Problems solved by technology

The commercial stroke processing software RAPID (rapidprocessing of perfusion and diffusion) can extract brain parameter maps of interest from MRI diffusion-weighted images (DWI) and perfusion-weighted images (PWI) (M.Straka, G.W.Albers, R.Bammer, Real -time diffusion-perfusion mismatch analysis in acute stroke, J. Magnetic Resonance Imaging, 32, 1024-1037, 2010), but it is difficult to solve the problem of accurate registration of DWI and ASL

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