A hand-held tubular bioprobe and its detection method in detecting organ activity

Abstract

The invention discloses a handheld tubular biological probe for micro organ activity detection, and a detection algorithm. The biological probe comprises a blood oxygen photoelectric sensor, signal transmission lines and a signal processing module, the signal transmission lines are led out from the back face of the blood oxygen photoelectric sensor, are gathered and then are connected to the signal processing module, a circle of light shield is arranged on the periphery of the blood oxygen photoelectric sensor, and the end, away from the blood oxygen photoelectric sensor, of the light shield is connected with a flexible or hard catheter rod; the signal transmission lines penetrate through the light shield and the interior of the catheter rod in sequence and are connected with the signal processing module fixed to the tail portion of the catheter rod. According to the detection algorithm, the blood oxygen saturation value average value, the blood oxygen waveform standard deviation and the pulsation frequency are calculated according to the measurement result of the biological probe, and then the activity of a micro organ is judged. The biological probe is suitable for detecting theactivity of in-vivo micro organs in an open operation environment, and is simple to operate and wide in application prospect.

Description

technical field [0001] The invention relates to the field of biomedicine, in particular to a hand-held tubular biological probe for in-situ online detection of organ activity and a detection method. Background technique [0002] The detection of the activity of small organs in the body has always been a major difficulty in the medical field, such as the detection of the activity of the parathyroid gland tissue. At present, there is no accurate qualitative judgment standard for the detection of the activity of the parathyroid gland tissue in medicine. Visually observe the color of the parathyroid gland tissue to judge its blood supply: if the parathyroid gland tissue appears light red, it is judged that its blood supply is normal, and it is retained; if the parathyroid gland tissue appears pale, it is judged that its blood supply Abnormal, remove it. Although intraoperative parathyroid hormone (PTH) measurement is a functional diagnostic tool during parathyroid surgery, it c...

AI Technical Summary

Problems solved by technology

However, these two traditional blood oxygen measurement devices cannot be used in the detection of small organ activity in the body, regardless of the structure of the measurement device or the measurement principle, mainly because:

[0004] (1) The size and shape of traditional blood oxygen measurement devices cannot go deep into the body through minimally invasive channels

As far as the measurement of parathyroid gland tissue is concerned, the shape of the parathyroid gland is an ellipsoid structure with a diameter of less than 1 cm, while the above two blood oxygen measurement devices are planar structures, and the contact surface area is much larger than that of the parathyroid gland tissue. It fits well with the parathyroid gland tissue, so accurate measurement data cannot be obtained, which in turn affects the determination of its activity

[0005] (2) The traditional blood oxygen measurement based on transmission optical measurement consists of separate light emitters and light receivers, which are respectively located on the opposite side of the test site, so a clamp-on measurement device is required, and the texture of small organs in the body is relatively relatively Soft, if a clamping structure is used, on the one hand, the size of the blood oxygen measurement device will be increased, and on the other hand, it will also squeeze the organs, thus affecting the accuracy of the signal and subsequent judgments

[0006] (3) When the internal environment is detected online, there is a large amount of blood contamination that affects the blood oxygen measurement results, and the activity of tiny organs in the body cannot be judged based on the absolute value of blood oxygen

However, because the device cannot isolate the interference of ambient light, it is only suitable for detection in a physiologically stable environment that is completely isolated from external ambient light, and is not suitable for open surgical environments.

Moreover, the device cannot fit well with tiny organs, the accuracy of the blood oxygen value is low, and it cannot be applied to the blood oxygen detection of specific tiny organs in the body

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