Cerebral perfusion weighted imaging method based on arterial spin labeling and variable delay time

A technology of arterial spin labeling and delay time, which can be used in diagnostic recording/measurement, medical science, telemetry patient monitoring, etc. It can solve the problems of high radio frequency energy and motion sensitivity, and achieve the effect of reducing sensitivity and small radio frequency energy deposition

Active Publication Date: 2020-08-18
SHENZHEN ANKE HIGH TECH CO LTD
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Problems solved by technology

[0004] In view of the above deficiencies in the prior art, the purpose of the present invention is to provide a brain perfusion weighted imaging method based on arterial spin labeling with variable delay time, aiming to sol

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  • Cerebral perfusion weighted imaging method based on arterial spin labeling and variable delay time
  • Cerebral perfusion weighted imaging method based on arterial spin labeling and variable delay time
  • Cerebral perfusion weighted imaging method based on arterial spin labeling and variable delay time

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[0026] The present invention provides a brain perfusion weighted imaging method based on arterial spin labeling with variable delay time. In order to make the objectives, technical solutions and effects of the present invention clearer and clearer, the present invention will be described in further detail below. It should be understood that the specific embodiments described herein are only used to explain the present invention, but not to limit the present invention.

[0027] When an exogenous contrast agent is used for magnetic resonance perfusion weighted imaging, it has the following disadvantages: contrast agent is required, which can cause damage to patients with poor renal function; because cerebral perfusion measures the blood in the capillary bed Parameters such as volume and blood flow require the exogenous contrast agent to pass through the brain area by bolus injection without entering the brain tissue. In actual operation, because many patients, especially the elderly...

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Abstract

The invention discloses a cerebral perfusion weighted imaging method based on artery spin labeling and variable delay time, wherein the method comprises the steps: applying 180-degree pulses to a marked area, and acquiring signals on an imaging layer by adopting a rapid sequence after t time to obtain an image signal scanned for the first time; applying 180-degree pulses to the marked area, aftert+(n-1)*m time, collecting signals on the imaging layer in a rapid sequence mode, and thus obtaining image signals scanned for the n time, wherein n is greater than or equal to 3; constructing animage signal intensity-time curve according to the n scanned image signals; and calculating the image signal intensity-time curve to obtain cerebral perfusion parameters. According to the method, twice scanning of marking and unmarking is not needed, so that the sensitivity to motion is reduced; the radio frequency energy deposition is small; brain perfusion parameters such as blood volume, bloodflow, average transfer time and arrival time can be generated.

Description

Technical field [0001] The present invention relates to the field of magnetic resonance sequence, in particular to a cerebral perfusion weighted imaging method based on arterial spin labeling with variable delay time. Background technique [0002] Magnetic resonance perfusion weighted imaging uses endogenous or exogenous contrast agents to measure a series of parameters such as blood flow and blood volume in the capillary bed in normal or diseased tissues. Exogenous contrast agents are generally paramagnetic contrast agents commonly used in magnetic resonance, such as gadolinium-based contrast agents, which can shorten blood t2 and t2 in the blood * Time, leading to the time between t2 and t2 * The signal of capillary blood vessels and adjacent tissues on the weighted image will be reduced, and the degree of signal reduction is proportional to the content of the intravascular contrast agent, so that the blood volume and blood flow in the unit volume of tissue can be calculated. [...

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Application Information

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IPC IPC(8): A61B5/026A61B5/00
CPCA61B5/0263A61B5/0042A61B5/72
Inventor 孙治国
Owner SHENZHEN ANKE HIGH TECH CO LTD
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