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Acne-removing vesicle composition as well as preparation method and application thereof

A technology of composition and vesicles, which is applied in the direction of drug combinations, pharmaceutical formulas, cosmetic preparations, etc., to achieve the effects of improved stability, simple preparation method, and good compatibility

Active Publication Date: 2020-10-23
泉后(广州)生物科技研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] At present, products for treating grade I-II acne generally only have one or two functions of regulating epidermal hyperkeratosis, oil control, sterilization, and anti-inflammation. Therefore, it is necessary to develop a product that can comprehensively remove acne

Method used

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  • Acne-removing vesicle composition as well as preparation method and application thereof
  • Acne-removing vesicle composition as well as preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0033] This example is an embodiment of the acne-removing vesicle composition of the present invention. The anti-acne vesicle composition of this embodiment includes the following components in parts by weight: 3 parts of active substances, 21.69 parts of vesicle components, and 75.31 parts of water;

[0034] Among them, the active substance is composed of papain, nicotinamide, zinc gluconate, caprylyl glycine, caprylyl glycol, linoleic acid and acetyl glucosamine, and the weight ratio of these seven active substances is papain: nicotinamide: glucosamine Zinc saccharate: caprylyl glycine: caprylyl glycol: linoleic acid: acetylglucosamine = 3.8:5:3:3.2:2.4:6.5:1.8;

[0035] Vesicle components are composed of emulsifier, co-emulsifier, cholesterol and hydrogenated lecithin, and their weight ratio is emulsifier:co-emulsifier:cholesterol:hydrogenated lecithin=4.5:15.7:0.24:1.25;

[0036] The emulsifier is composed of polyglyceryl-6 laurate and sanritan palmitate, and their weight...

Embodiment 2

[0043] This example is an embodiment of the acne-removing vesicle composition of the present invention. The anti-acne vesicle composition of this embodiment includes the following components in parts by weight: 0.1 parts of active substance, 3.2 parts of vesicle components, and 96.7 parts of water;

[0044] Among them, the active substance is composed of papain, nicotinamide, zinc gluconate, caprylyl glycine, caprylyl glycol, linoleic acid and acetyl glucosamine, and the weight ratio of these seven active substances is papain: nicotinamide: glucosamine Zinc saccharate: caprylyl glycine: caprylyl glycol: linoleic acid: acetylglucosamine = 3.8:5:3:3.2:2.4:6.5:1.8;

[0045] Vesicle components are composed of emulsifier, co-emulsifier, cholesterol and hydrogenated lecithin, and their weight ratio is emulsifier:co-emulsifier:cholesterol:hydrogenated lecithin=1:2:0.1:0.1;

[0046] The emulsifier is composed of polyglyceryl-6 laurate and sanritan palmitate, and their weight ratio is...

Embodiment 3

[0053] This example is an embodiment of the acne-removing vesicle composition of the present invention. The anti-acne vesicle composition of this embodiment includes the following components in parts by weight: 10 parts of active substances, 60 parts of vesicle components, and 30 parts of water;

[0054] Among them, the active substance is composed of papain, nicotinamide, zinc gluconate, caprylyl glycine, caprylyl glycol, linoleic acid and acetyl glucosamine, and the weight ratio of these seven active substances is papain: nicotinamide: glucosamine Zinc saccharate: caprylyl glycine: caprylyl glycol: linoleic acid: acetylglucosamine = 3.8:5:3:3.2:2.4:6.5:1.8;

[0055] Vesicle components are composed of emulsifier, co-emulsifier, cholesterol and hydrogenated lecithin, and their weight ratio is emulsifier:co-emulsifier:cholesterol:hydrogenated lecithin=15:35:5:5;

[0056] The emulsifier is composed of polyglyceryl-6 laurate and sanritan palmitate, and their weight ratio is poly...

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Abstract

The invention discloses an acne-removing vesicle composition as well as a preparation method and application thereof, and belongs to the field of cosmetics. According to the invention, seven active ingredients of papain, nicotinamide, zinc gluconate, capryloyl glycine, caprylyl glycol, linoleic acid and acetylchitosamine are combined, the acne problem is solved from four dimensions of epidermis excessive keratinization regulation, oil control, sterilization and inflammation resistance, a good treatment effect is achieved on acne vulgaris from the first level to the second level, and acne markscaused by acne inflammation and melanosis can be eliminated; besides, the seven active ingredients are embedded in the vesicles, so that the stability of the seven active ingredients can be improved,and the prepared acne-removing vesicle composition is stable, good in compatibility, good in effect, simple in preparation method and low in cost.

Description

technical field [0001] The invention belongs to the field of cosmetics, and relates to an acne-removing vesicle composition, a preparation method and application thereof. Background technique [0002] Acne is a chronic inflammatory skin disease of the pilosebaceous glands. The three common types of acne are acne vulgaris, rosacea, and acne inversa (commonly known as hidradenoid AI / HS in the United States). Acne vulgaris is caused by excessive activation and proliferation of keratinocytes in young and healthy hair follicle units; rosacea is caused by sun damage that weakens the upper part of hair follicle units; AI / HS is caused by the destruction of hair follicle units at the pilosebaceous junction It solves some acne vulgaris problems. [0003] From the skin microstructure of acne, the mechanism of acne is as follows: FPSU (pilosebaceous unit) structure is the basic unit of acne, consisting of follicular unit, hair unit and sebaceous unit. FPSU produces various substances ...

Claims

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Application Information

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IPC IPC(8): A61K8/73A61K8/66A61K8/67A61K8/365A61K8/27A61K8/44A61K8/34A61K8/36A61K8/63A61K8/55A61K8/39A61K8/49A61K8/14A61Q19/00A61Q17/00A61P17/10A61P29/00A61P31/02
CPCA61K8/736A61K8/66A61K8/675A61K8/365A61K8/27A61K8/44A61K8/345A61K8/361A61K8/63A61K8/553A61K8/39A61K8/4973A61K8/14A61Q19/00A61Q19/008A61Q17/005A61P17/10A61P29/00A61P31/02A61K2800/592A61K2800/56
Inventor 刘露张娇韩志东
Owner 泉后(广州)生物科技研究院有限公司
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