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Liquid workstation applied to biology

A workstation, biological technology, applied in the field of biology, can solve the problems of heavy workload, cumbersome experimental operation, pollution between samples, etc., to achieve highly automated pollution, improve extraction efficiency, and avoid pollution.

Pending Publication Date: 2021-01-12
AURORA DISCOVERY INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the prior art, the automatic liquid processing workstation and the liquid pipetting device in it mostly use a sliding friction pair mechanism to complete the vertical movement of the pipetting tip. The processing accuracy requirements are higher, it is difficult to guarantee
In addition, in the existing liquid pipetting devices, the positioning of the moving base of the liquid pipetting mechanism in the vertical direction of the rotating shaft is mostly constrained by the combination of splines and rollers, and the adjustment during the assembly process is complicated and the workload is relatively large.
[0005] In biological experiments, the establishment of nucleic acid extraction and PCR reaction systems generally requires multiple pipetting, which is cumbersome and limits the extraction efficiency of samples. There are more impurities, which need to be purified again and again to meet the requirements
And manual operation is easy to cause contamination between samples

Method used

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  • Liquid workstation applied to biology
  • Liquid workstation applied to biology
  • Liquid workstation applied to biology

Examples

Experimental program
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Effect test

Embodiment 1

[0032] see Figure 1-8 , in an embodiment of the present invention, a liquid workstation applied to biology includes a working platform 6, a working surface 3, a pipetting arm 1, and a moving rack 2. The working surface 3 is arranged on the working platform 6, and behind the working platform 6 An equipment box 60 is installed vertically on the top surface, and the pipetting arm 1 is installed on the top of the equipment box 60 through the x-axis, y-axis and Z-axis driving mechanism. It includes nine working trays arranged in a nine-square grid. The working trays are placed in turn from the inside to the outside and from left to right. The No. 1 gun tip adapter 31, the No. No. gun tip adapter 34, reagent tank carrier 35, temperature control adapter 36, magnetic bead mixer 4, magnetic bead separation disc 37 and heating shock disc 38;

[0033] The No. 1 gun tip adapter 31, the No. 2 gun tip adapter 32 and the No. 3 gun tip adapter 34 are placed with multi-standard gun tips, and...

Embodiment 2

[0044] The difference between this embodiment and Embodiment 1 is that the No. 1 tip adapter 31 , the No. 2 tip adapter 32 and the No. 3 tip adapter 34 can place 1000, 200, 100 and 50 μL tips according to different experiments. Preferably, we place a pipette tip of 1000 μL specification on No. 1 pipette tip adapter 31, place a pipette tip of 200 μL specification on No. 2 pipette tip adapter 32, and place a pipette tip of 1000 μL specification on No. 3 pipette tip adapter 34;

[0045] Wherein the sample collection carrier 33 in the working disk surface 3 is used to place the test to be tested. The sample collection carrier 33 shown is not limited to a standard 24-well plate, a standard 48-well plate, a standard 96-well plate and the like. Preferably, we place 24 EP centrifuge tubes on the sample collection carrier 33 .

[0046] The reagent tank carrier 35 in the working panel 3 of this embodiment, considering the usage habit of the user, the reagent bottle is put into the instr...

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PUM

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Abstract

The invention discloses a liquid workstation applied to biology. The liquid workstation comprises a working platform, a working disc surface, a liquid transfer arm and a disc transfer frame, wherein the liquid transfer arm is arranged right above the working disc surface through an x-axis driving mechanism, a y-axis driving mechanism and a Z-axis driving mechanism; the x axis of the liquid transfer arm is parallel to an equipment box; the working disc surface area comprises nine working disc positions which are arranged in a nine-grid manner; and a first gun head adapter, a second gun head adapter, a sample collection carrier, a third gun head adapter, a reagent tank carrier, a temperature control adapter, a magnetic bead mixer, a magnetic bead separation disc and a heating oscillation disc are sequentially arranged on the working disc positions from inside to outside and from left to right. The overall structure layout is very compact, an open kit is adopted, the liquid workstation issuitable for kits of various manufacturers, the extraction process is highly automatic, pollution is avoided, the extraction efficiency is improved, and high-quality and high-purity nucleic acid andother macromolecular products can be purified and extracted.

Description

technical field [0001] The invention specifically relates to the field of biology, in particular to a liquid workstation applied to biology. Background technique [0002] With the rapid development of life science technology, the research work of biochemical laboratories is faced with more complex research objects and an increasing number of samples. The traditional manual operation can no longer meet the high efficiency required in the process of high-throughput sample processing. , accuracy and safety, the automatic operation of some or the whole process in the experimental operation process has become an inevitable trend. [0003] Nucleic acid is the basic object of molecular biology research, and the extraction of nucleic acid is the most important and basic link in molecular diagnosis. There are many methods for extracting DNA or RNA from biological samples, such as the traditional organic solvent extraction method, as well as the silica gel column adsorption method, c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/00C12N15/10
CPCC12N15/1013
Inventor 梁洞泉张其峰
Owner AURORA DISCOVERY INC