Lipidosome as well as preparation method and application thereof

Abstract

The invention discloses lipidosome as well as a preparation method and application thereof. The lipidosome comprises the components of sugar alcohol, polyol, an emulsifier and a functional component.The preparation process of the lipidosome comprises the following steps of mixing sugar alcohol and polyol, uniformly stirring, adding the emulsifier and the functional component, stirring, and homogenizing uniformly to obtain the lipidosome. According to the lipidosome, the raw materials do not need to be mixed with the emulsifier in an aqueous solution environment, the use of a thickening agentis remarkably reduced, and the prepared liposome is uniform and stable and does not have obvious layering and oil separation phenomena. The process does not need sterilization or bacteriostasis and drying treatment on a product, effectively reduces the production procedures of the product, can effectively improve the stability of the product and prolong the shelf life of the product, and is suitable for direct oral administration of the product or pouring of various candy or drug dosage forms as a content.

Description

technical field [0001] The invention belongs to the field of food and medicine, and in particular relates to a liposome and its preparation method and application. Background technique [0002] In the food and pharmaceutical industries, it is usually necessary to make water-insoluble or low-water-soluble lipid raw materials into water-soluble or hydrophilic product forms to achieve the intended purpose and improve bioavailability. At present, the mainstream technology uses water as the carrier and adds various emulsifiers. The main function of emulsifiers is to increase the surface tension of liposomes so that they can better mix with water to form micromicelles. Commonly used emulsifiers include various types of fatty acids Glycerides, Gum Arabic, Alginic Acid, Sodium Caseinate, Gelatin, Phospholipids, etc. These traditional lipid emulsification processes require mixing lipid components with emulsifiers, water, etc., and then undergo processes such as homogenization, steri...

AI Technical Summary

Problems solved by technology

[0003] The traditional lipid emulsification process inevitably undergoes heat treatment, such as sterilization, heating and remelting in the freeze-drying process, etc. Since the emulsified lipid system is in a relatively balanced state, factors such as temperature, ionic strength, light, and time It will affect the stability system of the product, and then affect the stability and shelf life of the product