Pre-filling equipment for sterile solid medicine granules

Abstract

The invention discloses pre-filling equipment for sterile solid medicine granules, and relates to the field of automatic equipment. The pre-filling equipment comprises a workbench, a feeding vibrationdisc, a medicine granule dispersing mechanism, a weighing mechanism, a rubber plug press-fitting mechanism and a bottle body press-fitting mechanism. The pre-filling equipment achieves automation inthe whole process based on assembly line type filling and automatic weighing; compared with traditional manual filling, the filling efficiency and the weighing precision are remarkably improved, and operation errors are reduced; and in the whole filling process, solid medicine granules can be in good contact with a pre-filling needle tube and are not prone to scattering.

Description

technical field [0001] The invention belongs to the field of automation equipment, and in particular relates to a pre-filling equipment for aseptic solid medicine granules. Background technique [0002] Implants, liposomes, microspheres and other preparations are emerging types of preparations, which have long-acting sustained-release effects and are generally used for cavity, tissue or subcutaneous implantation. They are sterile solid controlled-release dosage forms and are a class of A controlled release system that can be surgically implanted or introduced through a needle. Traditional drug administration methods include oral administration, circulatory system administration, and mucosal administration, each of which has its own disadvantages, such as the first-pass elimination effect of oral administration, hemolytic effect of circulatory administration, and incomplete absorption of mucosal administration. This drug delivery method of implantable drug delivery overcomes...

AI Technical Summary

Problems solved by technology

[0003] Pre-filling technology is currently a commonly used aseptic production process for sterile preparations. At present, the pre-filling technology for liquid preparations has become mature, but for new aseptic solid preparations such as implants, liposomes, and microspheres At present, there is no matching equipment for pre-filling solid drug particles, and manual filling is mostly used, that is, the weighed solid drug particles are manually loaded into the pre-filled needle tube, and a rubber stopper is pressed on one end of the tube. Then press-fit it together with the rubber stopper into the vial. Since the pre-filled needle tube is a tubular structure with openings at both ends, the solid medicine particles in it fit with the gap and are easy to spill. Therefore, workers need to be careful in operation. This method is time-consuming. This seriously restricts the production efficiency, and the error of manual measurement is large, which increases the quality risk of the product

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