Method for preparing scald ointment by utilizing marine fish leftovers

A technology for scraps and scald ointment, which is applied in the directions of medical raw materials derived from fish feed, medical preparations with inactive ingredients, and medical preparations containing active ingredients, etc., can solve the problems of skin irritation, skin appearance, pigmentation and other problems , to prevent bacterial infection, good biocompatibility, and promote wound healing.

Active Publication Date: 2021-03-09
OCEAN UNIV OF CHINA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are many products for treating burns and scalds on the market. The curative effect of traditional Chinese medicine ointment is better than that of western medicine, especially for deep second-degree and third-degree burns. However, the composition of existing traditional Chinese medicine ointment for burns and scalds is quite different from that of human skin, which stimulates the skin and forms pigments. Pigmentation and scarring that affects the appearance of the skin, especially for dysfunction caused by severe infections that are difficult to resolve
Although there are many dressings, the water absorption, air permeability and antibacterial properties of dressings are poor

Method used

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  • Method for preparing scald ointment by utilizing marine fish leftovers

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Effect test

Embodiment 1

[0029] A kind of method utilizing sea fish leftovers to prepare scald ointment, it goes through the following process steps:

[0030] 1) Pretreatment of sea fish waste

[0031] a. Take the leftovers of marine fish, rinse them with distilled water, put them in a sterilizing pot, steam them at a temperature of 121°C and a pressure of 0.12 MPa for 18 minutes, take them out and cool them, crush them with a pulverizer and homogenize them, and adjust the concentration of the solids in the homogenate 70%;

[0032] b. Take the homogenate obtained in step a, add 2% collagenase and 4% lactobacillus by weight to the homogenate, grind at a temperature of 45°C for 130min, and perform ultrasonic treatment at the same time. The ultrasonic conditions are: ultrasonic frequency 12KHz, ultrasonic power 1.3W / cm 2 After grinding, add sterile water of equal quality, filter out solids, and prepare a reserve liquid for sea fish offal;

[0033] 2) Kelp pretreatment

[0034] Put the kelp in a pres...

Embodiment 2

[0042] A kind of method utilizing sea fish leftovers to prepare scald ointment, it goes through the following process steps:

[0043] 1) Pretreatment of sea fish waste

[0044] a. Take the leftovers of sea fish, rinse them with distilled water, put them into a sterilizing pot, steam them at a temperature of 115°C and a pressure of 0.1MPa for 15 minutes, take them out and cool them, grind them with a pulverizer and homogenize them, and adjust the concentration of the solids in the homogenate 65%;

[0045] b. Take the homogenate obtained in step a, add 2% collagenase and 3% lactobacillus by weight to the homogenate, grind at a temperature of 35°C for 90 minutes, and perform ultrasonic treatment at the same time. The ultrasonic conditions are: ultrasonic frequency 11KHz, ultrasonic power 0.6W / cm 2 After grinding, add sterile water of equal quality, filter out solids, and prepare a reserve liquid for sea fish offal;

[0046] 2) Kelp pretreatment

[0047] Put the kelp in a pre...

Embodiment 3

[0055] A kind of method utilizing sea fish leftovers to prepare scald ointment, it goes through the following process steps:

[0056] 1) Pretreatment of sea fish waste

[0057] a. Take the leftovers of marine fish, rinse them with distilled water, put them into a sterilizing pot, steam them at a temperature of 121°C and a pressure of 0.125 MPa for 20 minutes, take them out and cool them, crush them with a pulverizer and homogenize them, and adjust the concentration of the solids in the homogenate 80%;

[0058] b. Take the homogenate obtained in step a, add 2-3% collagenase and 3-5% lactobacillus by weight to the homogenate, grind at a temperature of 55°C for 150 minutes, and perform ultrasonic treatment at the same time. The ultrasonic conditions are: ultrasonic frequency 14KHz, ultrasonic Power 1.5W / cm 2 After grinding, add sterile water of equal quality, filter out solids, and prepare a reserve liquid for sea fish offal;

[0059] 2) Kelp pretreatment

[0060] Put the kel...

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Abstract

The invention discloses a method for preparing scald ointment by utilizing marine fish leftovers. The method solves the problems that the existing traditional Chinese medicine scald ointment stimulates the skin and easily forms pigmentation and scars. The method comprises the following steps of 1) pretreating the marine fish leftovers; 2) pretreating kelp; 3) preparing sea cucumber regeneration factors; 4) mixing scald ointment materials; and 5) preparing the scald ointment. According to the method disclosed by the invention, the marine fish leftovers are subjected to hydrothermal treatment and grinding coupling biological treatment, and active water-soluble components of fish bones are extracted; trace elements in the kelp are extracted through alkali washing of the kelp; and sea cucumbergrowth factors are separated by utilizing column chromatography, and then the sea cucumber growth factors are matched with glycerinum, chitosan, beer and fish oil, so that the scald ointment is obtained. All the components of the scald ointment disclosed by the invention are synergistic, wound healing and skin tissue regeneration are promoted, the biocompatibility is good, no side effect exists,and no scar is left on a wound part.

Description

technical field [0001] The preparation of the ointment of the present invention is, in particular, a method for preparing a scald ointment by utilizing leftovers of sea fish. Background technique [0002] Burns and scalds often occur in daily life. About 0.5% to 1% of the population in my country suffers from them every year, and deep burns and scalds account for one-tenth. Deep burns and scalds can damage human skin and subcutaneous tissue, leading to serious consequences such as human body ulceration and infection. If the wound is not treated in time, the infection will persist for a long time, and scabs will cause scars. In severe cases, it will affect the function of the limbs and bring huge mental trauma and physical damage to the patient. [0003] At present, there are many products for treating burns and scalds on the market. The curative effect of traditional Chinese medicine ointment is better than that of western medicine, especially for deep second-degree and third...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/616A61K36/03A61K36/899A61K47/10A61P17/02A61K9/06A61K31/047A61K31/722A61K35/60
CPCA61K35/60A61K36/03A61K35/616A61K31/047A61K31/722A61K36/899A61K9/06A61K47/10A61P17/02A61K2300/00
Inventor 李钰金毛相朝赵元晖薛长湖徐莹孙逊陈桂东董暄
Owner OCEAN UNIV OF CHINA
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