Traditional Chinese medicine composition for treating psoriasis vulgaris and preparation method thereof

A technique for psoriasis vulgaris and its composition, which is applied in the field of traditional Chinese medicine composition and its preparation for the treatment of psoriasis vulgaris, and can solve the problems of affecting the quality of life of patients, damage of skin barrier function, poor safety, etc.

Active Publication Date: 2021-03-19
FIRST AFFILIATED HOSPITAL HEILONGJIANG UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the treatment of psoriasis vulgaris, external treatment is an important means. In terms of western medicine treatment, currently available external drugs include tar preparations, glucocorticoids, retinoic acid, vitamin D 3 However, the disadvantages of these drugs are as follows: first, the long-term curative effect is poor, and often cause rebound or recurrent skin lesions after drug withdrawal, especially glucocorticoids can induce pustular or erythrodermic disease-type psoriasis; second, poor safety, tar preparations have a certain carcinogenic tendency; long-term and large-scale application of glucocorticoids can transform psoriasis vulgaris into pustular or erythrodermic psoriasis , instead aggravates the condition, and can cause side effects such as skin hirsutism, pigmentation, and skin atrophy; retinoic acid can affect the patient's blood lipid metabolism and affect children's development; vitamin D 3 Such drugs can increase blood calcium concentration after skin absorption and affect heart function; external application of immunosuppressants through epidermis can cause liver damage to a greater extent, and long-term topical application of skin immunosuppressants can cause local skin barrier function damage and induce A series of infections; third, the application population and site limitations, such as tar preparations are not used in pregnant women, patients with pustular and erythrodermic psoriasis, or patients with severe acne and folliculitis; glucocorticoids Do not apply to skin and mucous membranes, or patients with severe hypertension, diabetes, hypokalemia, and hypocalcemia; retinoic acid should not be used in special populations such as children and pregnant women; vitamin D 3 The class is not used for patients with severe heart disease and hypercalcemia; immunosuppressants are not used for the face, or for people with severe anemia, or women of childbearing age; Fourth, the cost is high, no matter which drug is used for a long time Both are higher than traditional Chinese medicine preparations
But the existing washing medicine for the treatment of psoriasis vulgaris has following shortcoming: one, the therapeutic pertinence of washing medicine is not strong, only for a certain one or some skin lesion performances of psoriasis, can not To achieve the purpose of breaking down one by one, if it only has the effect of clearing away heat and detoxification, although it can treat erythema, it cannot moisturize the skin and promote muscle growth; secondly, the external washing medicine can not take into account both subjective and objective symptoms, such as many external washing medicines can only Reach the effect of treating skin lesion, but do not have the effect of antipruritic etc., although patient's skin lesion alleviates to some extent, itching is unbearable at night, seriously affects patient's quality of life; After application, a series of corresponding symptoms such as skin lesions itching, burning, dryness or skin inflammation caused by irritation will be produced; fourth, external washing medicines cannot be applied to skin lesions accompanied by superficial damage, and the formula of the present invention can not only be applied For psoriatic skin lesions, it has a certain healing effect on psoriatic bleeding points or superficial skin lesions and ulcers

Method used

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  • Traditional Chinese medicine composition for treating psoriasis vulgaris and preparation method thereof
  • Traditional Chinese medicine composition for treating psoriasis vulgaris and preparation method thereof
  • Traditional Chinese medicine composition for treating psoriasis vulgaris and preparation method thereof

Examples

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preparation example Construction

[0020] The preparation method of the above-mentioned Chinese medicine composition for treating psoriasis vulgaris comprises the following steps:

[0021] Weigh 15-40 parts of black plum, 15-50 parts of saponins, 10-45 parts of Qingdai, 15-45 parts of arborvitae leaves, 10-40 parts of bletilla striata, 10-35 parts of Chutao leaves, mix and add water to fry boil, and collect the decoction to obtain the traditional Chinese medicine composition.

[0022] The above-mentioned traditional Chinese medicine composition can be further prepared into a pharmaceutically acceptable external preparation.

Embodiment 1

[0025] A traditional Chinese medicine composition for treating psoriasis vulgaris, which is composed of the following raw materials: 30g of black plum, 30g of saponins, 20g of Qingdai, 20g of orientalis leaves, 15g of bletilla striata, and 15g of Chutao leaves;

[0026] The preparation method of this Chinese medicine composition comprises the following steps:

[0027] Weigh 30g of ebony plum, 30g of saponin thorn, 20g of Qingdai, 20g of oriental cypress leaf, 15g of bletilla striata, and 15g of Chu peach leaf. decocting water, and collect the decoction.

[0028] The traditional Chinese medicine composition is used directly according to the method of external lotion, once a day.

Embodiment 2

[0030] A traditional Chinese medicine composition for treating psoriasis vulgaris. The difference from Example 1 is that the proportioning ratio is different. The traditional Chinese medicine composition provided by this example is made up of the following raw materials: 40g of ebony plum, 50g of Saponaria japonica, 45g of Qingdai, and arborvitae 45g leaves, 40g bletilla striata, 35g Chu peach leaves.

[0031] The preparation method of this Chinese medicine composition is identical with embodiment 1.

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly discloses a traditional Chinese medicine composition for treating psoriasis vulgaris. The traditional Chinese medicine composition comprises the following raw materials of, in parts by weight, 15-40 parts of dark plum, 15-50 parts of spina gleditsiae, 10-45 parts of indigo naturalis, 15-45 parts of cacumen biotae, 10-40 parts of bletilla striata and 10-35 parts of papermulberry leaf. With both objective symptoms, that is each skin lesion expression link including scale, papule, erythema, punctate hemorrhage and new flesh non-growth which are simultaneously visible from the outside to the inside of psoriasis vulgaris, and subjective symptom of pruritus considered in combination, the traditional Chinese medicine composition for treating psoriasis vulgaris provided by the invention aims to treat both symptoms together.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and specifically discloses a traditional Chinese medicine composition for treating psoriasis vulgaris and a preparation method thereof. Background technique [0002] Psoriasis is one of the common clinical skin diseases, and with changes in the environment, diet, and lifestyle, the incidence of psoriasis is increasing year by year, and the disease can occur in both men, women, and children, and has a certain genetic Sex, the current incidence of the population also has a tendency to expand to adolescents. At the same time, the disease is more common in the north than in the south, and it is more severe in winter and lighter in summer. Especially the long course of the disease and repeated attacks have brought great psychological and mental pressure to the patients. [0003] Clinically, psoriasis can be divided into two types: common type and special type. Among them, special ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61P17/06
CPCA61K36/736A61K36/483A61K36/704A61K36/315A61K36/195A61K36/14A61K36/898A61K36/60A61P17/06A61K2300/00
Inventor 安月鹏王姗姗
Owner FIRST AFFILIATED HOSPITAL HEILONGJIANG UNIV OF CHINESE MEDICINE
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