Kit for evaluating effect of 131I on treating differentiated thyroid cancer

A thyroid cancer and kit technology, which is applied to the determination/inspection of microorganisms, biochemical equipment and methods, DNA/RNA fragments, etc., can solve the problems of decreased iodine absorption capacity, no clear determination, and poor radiotherapy, etc. Achieve the effect of less non-specific amplification, overcoming mutual interference, and high uniformity
CN112646894AInactive Publication Date: 2021-04-13润安医学科技(苏州)有限公司
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
润安医学科技(苏州)有限公司
Publication Date
2021-04-13
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a primer and kit for evaluating the effect of 131I on treating differentiated thyroid cancer. The kit can be used for simultaneously detecting the variation of nine gene loci of a BRAF gene, a TERT gene, an HRAS gene and an NRAS gene, and the variation of the gene loci is closely related to the treatment effect of 131I on differentiated thyroid cancer. Therefore, when the kit is used for detecting a sample of a patient, a doctor can be assisted in scientifically evaluating the clinical effect of treating a differentiated thyroid cancer patient by using 131I, a basis is provided for making a precise treatment scheme of the patient, and the kit undoubtedly has very important clinical use value.
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Description

technical field

[0001] The invention relates to the field of molecular biology technology, in particular to a method for evaluating 131 I kit for treating differentiated thyroid cancer efficacy. Background technique

[0002] Papillary thyroid carcinoma (PTC) and follicular thyroid carcinoma (FTC) account for more than 90% of thyroid cancers, because they retain the function of thyroid follicular epithelial cells to a certain extent, such as sodium The expression of iodide transporter (sodium iodide symporter, NIS), the ability of iodine uptake, the ability of secreting thyroglobulin (thyroglobulin, Tg), the growth mode dependent on thyroid-stimulating hormone (thyroid-stimulating hormone, TSH), etc. It is called differentiated thyroid cancer (differentiated thyroid cancer, DTC). The increased incidence of DTC, especially PTC, is the main factor leading to the increase in the incidence of thyroid cancer in recent years. 131 I treatment of differentiated thyroid cancer (DTC)...

Claims

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