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Cavitation device for preparing palm oil-based submicron emulsion

An oil-based, cavitation technology, applied in mixers with rotary stirring devices, chemical/physical/physical-chemical processes using energy, transportation and packaging, etc., can solve the problems of low cavitation efficiency, product pollution, processing capacity Small problems such as high cavitation efficiency, convenient operation, and the effect of promoting the formation of arterial plaques

Inactive Publication Date: 2021-04-30
SHANDONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] CN210473997U disclosed "monomer recovery device in the emulsion preparation process" and CN210544522U disclosed "nano new material preparation emulsion mixing agitator" is by mechanical crushing, energy consumption is large, cost is high, and long-term operation can produce a large amount of wear and tear, causing product contamination
CN209885778U discloses " impact flow-hydraulic cavitation synergistically strengthens the device for preparing chitosan antibacterial nano-microspheres ", is made of impact flow chamber and two Venturi tubes symmetrically connected on both sides of impact flow chamber, although it has It has the advantages of simple structure and low energy consumption, but has the problems of small processing capacity and low cavitation efficiency

Method used

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  • Cavitation device for preparing palm oil-based submicron emulsion
  • Cavitation device for preparing palm oil-based submicron emulsion
  • Cavitation device for preparing palm oil-based submicron emulsion

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Embodiment Construction

[0032] The present invention prepares the cavitation device of palm oil-based submicron emulsion, such as figure 2 As shown, it includes a stator 9 , a rotor 13 , an ultrasonic probe 10 , an ultrasonic transducer 11 and a rotating shaft 4 . The stator 8 is a closed cylinder with stator end covers 7 arranged on both sides. The inner diameter of the stator is 500mm, the length is 500mm, and the wall thickness is 40mm. The stator end cover 7 is provided with an angular contact ball bearing 5 inside, and a sealing cover 2 is provided outside. The sealing cover 2 is connected with the sealing end cover 3, and a sealing washer 8 is provided at the connection, so that a sealed cavitation cavity is formed inside the stator. The inner wall of the stator is an irregular wall surface with a surface roughness of 0.05 mm, which is conducive to strengthening the cavitation effect. The inner wall of the stator 8 is equipped with an ultrasonic transducer 11 and an ultrasonic probe 10. The ul...

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Abstract

The invention provides a cavitation device for preparing a palm oil-based submicron emulsion. The cavitation device comprises a stator, a rotor, ultrasonic transducers and a rotating shaft, wherein the stator is provided with a feeding port, a discharging port and an oxidizing agent conveying pipe, the rotating shaft is installed in the stator, the rotor is arranged in the stator, the rotor is fixedly connected with the rotating shaft, blades are distributed on the rotor, and cavitation holes are distributed in the blades. According to the invention, palm oil is used as a dispersion phase and deionized water is used as a continuous phase to prepare an oil-in-water submicron emulsion; a crude emulsion enters the stator, liquid flow in a stator cavitation cavity is coupled with rotor vibration to achieve a strong cavitation effect; through combination of an ultrasonic probe, hydraulic cavitation and ultrasonic cavitation, cavitation efficiency is improved, energy input is much lower; and thus, the device has great potential in the aspect of emulsion preparation.

Description

technical field [0001] The invention relates to a device for preparing palm oil-based submicron emulsion, in particular to a device for preparing palm oil-based submicron emulsion by using cavitation technology. Background technique [0002] Submicron emulsions can incorporate lipophilic and hydrophilic drugs into the oil phase, increasing their solubility and local bioavailability while minimizing the side effects of effective drugs, so submicron emulsions are used as a treatment for various pain and Colloidal drug carriers on diseases have attracted more and more attention from the medical community. Compared with traditional emulsions, submicron emulsions have higher pharmacological activity and site-specific drug delivery capabilities. Good carrier for drug delivery. [0003] During the emulsification process, extremely high shear force and extremely high energy input are required to break the droplets of the premixed emulsion from micron to submicron or nanoscale, the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01J19/10B01F11/02B01F7/00B01F3/08
CPCB01J19/10B01J19/0053B01J19/0066B01F23/43B01F23/41B01F27/40B01F31/80
Inventor 陈颂英孙逊魏雪松王晓阳王梦洁
Owner SHANDONG UNIV
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