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Jingulian traditional Chinese medicine composition and preparation method thereof

A composition, the technology of golden bone lotus, is applied in the direction of drug combination, medical formula, antipyretic, etc., which can solve the problems of complex prescription, slow effect, side effects, etc., to achieve enhanced coordination interaction, good therapeutic effect, no Toxic effects

Active Publication Date: 2021-06-29
GUIZHOU YIBAI PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, Chinese patent CN108159315A discloses a capsule drug for treating gout and its preparation method. There are 17 kinds of Chinese herbal medicines, such as kernel, Smilax smilax, Rhizoma chinensis, Triangle wind, Mulberry branch, Polygonum cuspidatum, Streptococcus chinensis, Caterpillar vine, Chuanshanlong, Daxueteng, and Alisma. Complex, the active ingredient is not clear
Another example is Chinese patent CN111568958A disclosed a kind of traditional Chinese medicine tincture for treating joint soft tissue damage and its preparation method and application. It is believed that "the medicine is three-point poison". If it is not properly compatible and processed, it will also produce side effects during the treatment. Moreover, the active ingredients obtained in the extraction process of Chinese medicinal materials are not clear, and the precise dosage cannot be used. Generally, external use of traditional Chinese medicine, The dosage is large and the effect is slow. It can be seen that it is very meaningful to improve the existing marketed products, clarify and make full use of the effective active ingredients of the components. It is an important part of the modernization of traditional Chinese medicine. Necessary exploration path for safe and effective drug quality control
[0004] Through clinical use and groping, the inventor conducted research on the active ingredients of the composition of Rhododendron japonicus, changed the traditional thinking of using Chinese medicinal raw materials, invented a Chinese medicinal composition using the active ingredients of Chinese medicinal materials, and clarified the active ingredients of the prescription. Accurate dosage, so as to overcome the defect that most of the existing products have many formula ingredients, and the primary and secondary effects are not obvious; or the product has many effects, but the actual effect is not ideal.

Method used

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  • Jingulian traditional Chinese medicine composition and preparation method thereof
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  • Jingulian traditional Chinese medicine composition and preparation method thereof

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Effect test

Embodiment 1

[0026] Embodiment 1 Preparation of Jingulian Capsules of the present invention

[0027] Weigh 253mg of albagoside A, 45mg of fumaric acid, 360mg of lirioside, 1.5g of total saponins, 50mg of star anise, and 100g of starch;

[0028] Preparation method: Weigh each monomer component according to the amount, mix evenly, microwave dry, and control the microwave at 2540MHz, sieve the mixture with 100 mesh, add starch, mix evenly, put it into hollow capsules, and obtain 1000 golden bone lotus capsules.

[0029] Specification: 0.1g / grain;

[0030] Usage: take orally, 2 capsules at a time, 3 times a day.

Embodiment 2

[0031] Embodiment 2 Preparation of Jingulian Capsules of the present invention

[0032] Weigh 250mg of albagoside A, 38mg of fumaric acid, 365mg of lirioside, 1.2g of total saponins, 50mg of star anise base, and 100g of starch;

[0033] Preparation method: Weigh each monomer component according to the amount, mix evenly, microwave dry, and control the microwave at 2540MHz, sieve the mixture with 100 mesh, add starch, mix evenly, put it into hollow capsules, and obtain 1000 golden bone lotus capsules.

[0034] Specification: 0.1g / grain;

[0035] Usage: take orally, 2 capsules at a time, 3 times a day.

Embodiment 3

[0036] Embodiment 3 Preparation of Jingulian Tablets of the present invention

[0037] Weigh 255 mg of albagoside A, 40 mg of fumaric acid, 370 mg of lirioside, 1.8 g of total saponins, 50 mg of star anise base, 150 g of starch, and 100 g of dextrin;

[0038] Preparation method: Weigh each monomer component according to the amount, mix evenly, microwave dry, microwave control at 2540MHz, sieve the mixture with 100 mesh, add starch and dextrin, mix well, granulate with 10% starch slurry, dry and granulate Compress the tablet to obtain 1,000 tablets of the golden bone lotus.

[0039] Specification: 0.25g / piece;

[0040] Usage: take orally, 2 tablets at a time, 3 times a day.

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PUM

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Abstract

The invention relates to a Jingulian traditional Chinese medicine composition and a preparation method thereof. The composition is composed of active ingredients of gaultheria yunnanensis, schefflera kwangsiensis, sargentgloryvine stem, psammosilene tunicoides and alangium platanifolium. A composition medication prescription is screened through reasonable monarch, minister, assistant and guide; the effects of dispelling wind, removing dampness, soothing channels and activating collaterals of gaultheria yunnanensis and sargentgloryvine stem are mainly exerted; the traumatic fracture treatment effect of schefflera kwangsiensis, the toxin resolving and swelling dispersing effect of psammosilene tunicoides and the blood stasis dissipating and pain relieving effect of alangium platanifolium are combined; and, according to the medication dosage of a specific proportion, drugs in the prescription of the whole composition reach a synergistic effect in a combined manner. Compared with the prior art, the traditional Chinese medicine composition in the invention has the advantages that: the effective monomer components of the medicinal materials are utilized to secondarily develop and research the formula of Jingulian capsules, so that the effects of treating rheumatic diseases, joint inflammation, lung injury, infectious inflammation and the like are improved, the therapeutic effects of the medicine are exerted to the most extent, drug dependence is not generated, and toxic and side effects are avoided.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine compositions, in particular to a golden lotus traditional Chinese medicine composition and a preparation method thereof. Background technique [0002] Since the 1990s, under the guidance of relevant policies, we have vigorously developed and researched ethnic medicine preparations, successively developed more than 200 private, private and individual ethnic medicine institutions, and developed nearly 200 ethnic medicine prescriptions, among which the national There are 154 standard ethnic medicines, and a number of ethnic pharmaceutical enterprises have been produced at the same time. Now there are more than 70 pharmaceutical companies in Guizhou Province, producing more than 160 varieties of Miao medicines, including 154 varieties with national approved names. The annual output value started from zero in the early 1990s and grew at an average annual rate of more than 20%, reaching more...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048A61K31/191A61K31/704A61K31/4545A61K36/45A61K36/25A61K36/185A61K36/36A61P19/02A61P29/00
CPCA61K31/191A61K31/704A61K31/7048A61K31/4545A61K36/45A61K36/25A61K36/185A61K36/36A61P19/02A61P29/00A61K2300/00
Inventor 窦啟玲李勇军蒲健黄勇郑林谭丹
Owner GUIZHOU YIBAI PHARMA CO LTD
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