High-frequency magnetocaloric device for magnetocaloric genetic research on cells

Abstract

The invention discloses a high-frequency magnetocaloric device for activating an ion channel in a cell. The high-frequency magnetocaloric device comprises a power supply unit (1), a high-frequency inverter unit (2), a current amplification resonance unit (3), a multi-layer induction coil unit (4) and a signal control unit (5) which are connected in sequence, wherein the power supply unit (1) provides energy for a high-frequency inverter main circuit, the high-frequency inverter unit (2) converts a direct-current input signal into a high-frequency alternating-current signal and outputs the signal to the current amplification resonance unit (3), the current amplification resonance unit (3) amplifies the input alternating-current signal by two times and outputs the amplified alternating-current signal the multi-layer induction coil unit (4) and the signal control unit (5), the multi-layer induction coil unit (4) converts the alternating-current signal into a magnetic field signal through high-frequency resonance, and the signal control unit (5) scans driving frequency and outputs a feedback control signal to the high-frequency inverter unit (2) through LabVIEW software programming.

Description

technical field [0001] The invention relates to the field of magneto-thermal technology, in particular to a magnetic field generating device for activating heat-sensitive cell ion channels in the research of cell magneto-thermogenetics. [0002] technical background [0003] Magnetogenetics is the discipline of modulating neuronal activity. In recent years, magnetothermal genetics, which utilizes the magnetocaloric effect of magnetic nanoparticles to excite cellular ion channels to achieve the goal of regulating neural activity, has become one of the research hotspots. As the core tool of magnetocaloric genetics, magnetocaloric devices will directly affect the effect of magnetocaloric genetics due to the characteristics of the magnetic field they generate. The development and improvement of magnetocaloric devices is a necessary condition for promoting the development of magnetocaloric genetics research. [0004] High-frequency magnetothermal devices used in cell magnetotherm...

AI Technical Summary

Problems solved by technology

Its disadvantage is that it is difficult for ferrite to generate a stable high-frequency magnetic field due to material and process limitations, and its high-frequency performance is poor.

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