Preparation method of active ingredients in pleurospermum plant and application thereof in preparation of anti-inflammatory drugs

A technology of active ingredients and ridges, which is applied in the field of separation and purification of active ingredients in natural plants, can solve problems such as the separation and research of phytochemical separation components of P.
CN113277938AActive Publication Date: 2021-08-20QILU UNIV OF TECH
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
QILU UNIV OF TECH
Publication Date
2021-08-20

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Abstract

The invention relates to the technical field of separation and purification of active ingredients in natural plants, in particular to a preparation method of active ingredients in umbelliferae pleurospermum plant P.candollei. P.candollei is firstly extracted by adopting alcohol extraction to obtain a crude extract, the crude extract is then separated by adopting high-speed counter-current chromatography, a solvent system adopted by the high-speed counter-current chromatography is an n-hexane / ethyl acetate / methanol / water two-phase solvent system, an upper phase and a lower phase are taken before the high-speed counter-current chromatography is used, the upper phase is used as a stationary phase, and the lower phase is used as a mobile phase, and thefollowing compound monomers as described in the specification are obtained. The separation and purification method established by the invention realizes successful separation of nine monomer ingredients in the P.candollei plant, the purity of each obtained monomer is greater than 98%, and the separation and purification effects are good; the compounds 7 and 8 obtained through separation and purification can effectively inhibit NO generation.
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Description

technical field

[0001] The invention relates to the technical field of separation and purification of active ingredients in natural plants, in particular to a method for preparing the active ingredients of plants of the genus Piperia and its application in the preparation of anti-inflammatory drugs. Background technique

[0002] The information disclosed in this background section is only intended to increase the understanding of the general background of the present invention, and is not necessarily to be regarded as an acknowledgment or any form of suggestion that the information constitutes the prior art already known to those skilled in the art.

[0003] Celery belongs to the Umbelliferae family and has analgesic, anti-inflammatory and anti-malarial properties, and is also used as a condiment and herbal perfume. In Chinese folk medicine, celery is used as a diaphoretic, analgesic, and antipyretic. A variety of chemical constituents have been found from plants of the gen...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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