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Compound Phellodendron composition, compound Phellodendron spray preparation, preparation method and use

A spray and cork technology, applied in the field of medicine, can solve the problems of difficulty in obtaining the use effect, volatile skin absorption effect and poor stability, and achieve the effect of improving the treatment effect, improving the skin absorption performance, and maintaining the effect.

Active Publication Date: 2022-03-15
SHANDONG HANFANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But when the compound Phellodendron phellodendron liquid coating is directly made into a spray for the skin after changing the preparation, there are also problems of volatility, skin absorption effect and poor stability, and it is difficult to obtain the expected use effect

Method used

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  • Compound Phellodendron composition, compound Phellodendron spray preparation, preparation method and use
  • Compound Phellodendron composition, compound Phellodendron spray preparation, preparation method and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] This Compound Phellodendron Spray is prepared with the following ingredients:

[0040] Forsythia 80g, Phellodendron 40g, honeysuckle 40g, dandelion 40g and centipede 2.4g are decocted with water for three times, the first time for 1 hour, the second time for 45 minutes, the third time for 30 minutes, combine the decoction, filter, and filtrate Concentrate to a clear paste with a relative density of 1.10-1.15 (50°C), add ethanol to make the alcohol content reach 70%, let it stand for 24 hours, filter, and concentrate the filtrate under reduced pressure until it has no alcohol smell; add menthol 1.6 g; mix; get composition;

[0041] The following accessories: Bletilla striata gum 30g, sodium hyaluronate 8g, Span 10g, glycerin 80g, potassium sorbate 1.5g, sodium bisulfite 1.5g, mix well, add to the aforementioned composition, add water to 1000g, stir well , filtered, and divided into a spray device to obtain a compound Phellodendron spray.

Embodiment 2

[0043] This Compound Phellodendron Spray is prepared with the following ingredients:

[0044] Forsythia 100g, Cork Phellodendron 50g, Honeysuckle 50g, Dandelion 50g, and Centipede 4g five-flavored raw materials are decocted in water three times, the first time is 1 hour, the second time is 45 minutes, and the third time is 30 minutes. Combine the decoction, filter, and concentrate the filtrate To a clear paste with a relative density of 1.10-1.15 (50°C); add 2 g of menthol as an auxiliary material, and mix well; obtain a composition;

[0045] The following auxiliary materials: 40g of bletilla striata gum, 5g of sodium hyaluronate, 15g of Span, 100g of glycerin, 2g of potassium sorbate, 1.5g of sodium bisulfite, mix well and add to the aforementioned composition, add water to 1000g, stir well, filter After that, put it into a spray device to get the compound Phellodendron cortex spray.

Embodiment 3

[0047] This Compound Phellodendron Spray is prepared with the following ingredients:

[0048] Forsythia 80g, cork cork 40g, honeysuckle 40g, dandelion 40g and centipede 2.4g five-flavor raw materials plus 70% ethanol aqueous solution decoction three times, the first time for 1 hour, the second time for 45 minutes, the third time for 30 minutes, combined decoction, Filtrate, concentrate the filtrate under reduced pressure until it has no alcohol smell, add 1 g of menthol, and mix well; the composition is obtained;

[0049]The following auxiliary materials: Bletilla striata gum 20g, sodium hyaluronate 5g, Span 10g, glycerin 50g, potassium sorbate 1.0g, sodium bisulfite 1.5g, mix well and add to the aforementioned composition, add water to 1000g, stir well, Filtrate, divide and put into the spraying device, obtain compound Phellodendron Phellodendri spray.

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Abstract

The invention relates to the technical field of medicine, in particular to a compound phellodendron composition, a compound phellodendron spray preparation, a preparation method and an application. The compound Phellodendron phellodendron composition is prepared from raw materials and auxiliary materials, and the auxiliary materials include menthol, bletilla striata gum and sodium hyaluronate. The compound phellodendron composition increases the skin protection effect and improves the absorption effect by adding auxiliary materials such as menthol, bletilla striata gum, and sodium hyaluronate on the basis of the existing compound phellodendron liquid paint; it is especially made into a compound phellodendron spray The preparation is convenient and safe to use, fast to absorb, stable in product, and has remarkable curative effect on insect bite dermatitis.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a compound phellodendron composition, a compound phellodendron spray preparation, a preparation method and an application. Background technique [0002] Insect bite dermatitis, also known as papular urticaria, is a common skin disease in children in summer and autumn. There are many insects that cause insect bite dermatitis, such as mosquitoes, bedbugs, fleas, mites, midges (small black worms), etc. In addition, some caterpillars, such as mulberry caterpillars and thorny caterpillars, can also cause symptoms when their venomous burrs penetrate the skin. The treatment after mosquito bites is generally based on anti-allergic and anti-itching. Most of the existing drugs used to relieve itching and reduce swelling from mosquito bites are western medicines, such as Piyanping and Ailuosong, etc. Long-term use will not only produce drug resistance, but also may cause pigmentation on t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K47/36A61K47/10A61K36/756A61K9/12A61P17/00A61P17/02A61K35/648
CPCA61K36/634A61K36/756A61K36/355A61K36/288A61K35/648A61K47/36A61K47/10A61K9/0014A61P17/00A61P17/02A61K9/12A61K2236/331A61K2236/333A61K2236/53A61K2300/00
Inventor 任松鹏马河相恒云韩德凤任燕茹徐凤霞
Owner SHANDONG HANFANG PHARMA