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Vaccine traditional Chinese medicine composition for treating infectious diseases through transdermal administration and preparation method thereof

A technology for infectious diseases and compositions, which is applied in the field of transdermal administration of vaccines and traditional Chinese medicine compositions for treating infectious diseases and its preparation. It can solve problems such as undiscovered problems, and achieve the effects of reduced dosage, obvious curative effect, and quick effect

Pending Publication Date: 2021-09-07
王琳扬 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After searching, no precedents have been found for transdermal administration of BCG vaccine combined with traditional Chinese medicine in the treatment of pneumonia and other infectious diseases

Method used

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  • Vaccine traditional Chinese medicine composition for treating infectious diseases through transdermal administration and preparation method thereof
  • Vaccine traditional Chinese medicine composition for treating infectious diseases through transdermal administration and preparation method thereof

Examples

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Effect test

Embodiment 1

[0027] The traditional Chinese medicine composition for percutaneous administration of vaccines for treating infectious diseases, including whole BCG vaccine (specification 0.5mg / 1mL) and the following Chinese medicine raw materials in parts by weight: 10 parts of Coptis chinensis, 3 parts of Phellodendron Phellodendri, 5 parts of Scutellaria baicalensis, 20 parts of rhubarb, and aloe vera 2 parts, 5 parts of dandelion, 10 parts of Radix Isatidis, 6 parts of honeysuckle, 10 parts of forsythia, 5 parts of Folium Folium, 5 parts of Viola, 5 parts of Andrographis paniculata, 1 part of Bupleurum, 3 parts of Chrysanthemum, 3 parts of Shandougen 4 parts, 4 parts of Artemisia annua and 3 parts of Danshen.

Embodiment 2

[0029] A traditional Chinese medicine composition for percutaneous administration of vaccines for treating infectious diseases, including whole BCG vaccine (specification 0.5mg / 1mL) and the following Chinese medicine raw materials in parts by weight: 12 parts of Coptis chinensis, 5 parts of Phellodendron Phellodendri, 5 parts of Scutellaria baicalensis, 13 parts of rhubarb, and aloe vera 2 parts, 5 parts of dandelion, 8 parts of Radix Isatidis, 7 parts of honeysuckle, 7 parts of forsythia, 3 parts of Daqingye, 5 parts of Viola chinensis, 8 parts of Andrographis paniculata, 3 parts of Bupleurum, 8 parts of Chonglou, 3 parts of Shandougen 2 parts, 2 parts of Artemisia annua and 4 parts of Danshen.

Embodiment 3

[0031] A traditional Chinese medicine composition for percutaneous administration of vaccines for treating infectious diseases, including whole BCG vaccine (specification 0.5mg / 1mL) and the following traditional Chinese medicine raw materials in parts by weight: 12 parts of Coptidis Rhizome, 9 parts of Phellodendron Phellodendri, 3 parts of Scutellaria baicalensis, 13 parts of Rheum officinalis, and aloe vera 3 parts, 6 parts of dandelion, 8 parts of Radix Isatidis, 6 parts of honeysuckle, 12 parts of forsythia, 3 parts of Folium Folium, 6 parts of Viola chinensis, 3 parts of Andrographis paniculata, 2 parts of Bupleurum, 3 parts of Chonglou, 1 part of Shandougen 2 parts, 2 parts of Artemisia annua and 8 parts of Danshen.

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PUM

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Abstract

The invention discloses a vaccine traditional Chinese medicine composition for treating infectious diseases through transdermal administration. The vaccine is bacillus calmette guerin vaccine, and the traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials in parts by weight of 0-20 parts of coptis chinensis, 5-20 parts of rheum officinale, 0-9 parts of aloe, 0-16 parts of dandelion, 8-20 parts of isatis root, 6-20 parts of flos lonicerae, 5-20 parts of fructus forsythiae, 0-8 parts of andrographis paniculata, 1-10 parts of radix bupleuri, 2-11 parts of artemisia apiacea, 0-9 parts of cortex phellodendri and 0-9 parts of scutellaria baicalensis. According to the vaccine, transdermal administration is realized in a manner of the acillus calmette guerin vaccine and traditional Chinese medicines, a painful acillus calmette guerin vaccine intradermal injection method is replaced, the traditional Chinese medicine composition has obvious curative effects on various infectious diseases such as amygdalitis, pneumonia, nasosinusitis, appendicitis, otitis media, cholecystitis, influenza and the like, the treatment period is short and is 2-11 days, the traditional Chinese medicine composition is simple to use, injection and medicine taking are not needed, side effects are avoided, the effect is quick, and the traditional Chinese medicine replaces antibiotics.

Description

technical field [0001] The invention relates to the technical field of transdermal administration of pharmaceutical compositions, in particular to a traditional Chinese medicine composition for transdermal administration of vaccines for treating infectious diseases and a preparation method thereof. Background technique [0002] Transdermal delivery is a method by which drugs are absorbed through the skin. After the drug is applied to the skin, it passes through the stratum corneum, diffuses through the skin, and is absorbed into the systemic circulation by capillaries or lymphatic vessels, which is called percutaneous absorption or transdermal absorption. Transdermal drug delivery has its unique advantages. For example, transdermal administration can avoid the first-pass effect of the liver and the degradation of the drug in the gastrointestinal tract, and the absorption of the drug is not affected by gastrointestinal factors, reducing the individual differences in medicati...

Claims

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Application Information

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IPC IPC(8): A61K39/04A61K36/896A61K36/886A61K9/00A61K47/02A61K47/10A61K47/22A61P1/00A61P11/04A61P27/16A61P11/00A61P11/02A61P1/16A61P31/16A61P29/00
CPCA61K39/04A61K36/718A61K36/708A61K36/896A61K36/886A61K36/288A61K36/195A61K36/315A61K36/355A61K36/634A61K36/19A61K36/233A61K36/282A61K36/756A61K36/539A61K9/0014A61K47/10A61K47/22A61K47/02A61P1/00A61P11/04A61P27/16A61P11/00A61P11/02A61P1/16A61P31/16A61P29/00A61K2039/54A61K2300/00
Inventor 王九生
Owner 王琳扬
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