Mass spectrum interface structure and mass spectrum analyzer

An interface structure and mass spectrometry technology, applied in the field of mass spectrometry, can solve problems such as difficult operation and single measurement dimension

Pending Publication Date: 2021-09-14
深圳市卓睿通信技术有限公司
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  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] The purpose of the embodiments of the present invention is to provide a mass spectrometry interface structure to solve the technical problems of single measurement dimension and difficult operation when measuring the structure of protein molecules in the prior art

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  • Mass spectrum interface structure and mass spectrum analyzer
  • Mass spectrum interface structure and mass spectrum analyzer
  • Mass spectrum interface structure and mass spectrum analyzer

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Embodiment Construction

[0023] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

[0024] It should be noted that when an element is referred to as being “fixed” or “disposed on” another element, it may be directly on the other element or be indirectly on the other element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or indirectly connected to the other element.

[0025] It is to be understood that the terms "length", "width", "top", "bottom", "front", "rear", "left", "right", "vertical", "horizontal", "top" , "bottom", "inner", "outer" and other indicated orientations...

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Abstract

The invention provides a mass spectrum interface structure and a mass spectrum analyzer. The mass spectrum interface structure comprises a metal electrode, an electrospray ionization spray needle, a metal plate and an analyzer, the metal electrode is connected to the tail end of the electrospray ionization spray needle, and the head end of the electrospray ionization spray needle is provided with a nozzle and is arranged right opposite to the metal plate. The metal electrode and the metal plate have positive voltage difference, so that ions of the electrospray ionization spray needle are sprayed out from the nozzle and generate blocking current pulses, and the electrospray ionization spray needle is electrically connected with the analyzer, so that the analyzer analyzes the blocking current pulses and obtains the sizes of the ions. According to the mass spectrum interface structure and the mass spectrum analyzer provided by the invention, ions in the electrospray ionization spray needle are sprayed out from the nozzle under the action of voltage, when ions with the size equivalent to that of the nozzle are sprayed out, the blocking current pulse is generated, and the length and the width of the ions can be calculated through the signal amplitude and the blocking time of the blocking current pulse, so the specific size of the ions is obtained.

Description

technical field [0001] The invention belongs to the technical field of mass spectrometry, and more specifically relates to a mass spectrometer interface structure and a mass spectrometer. Background technique [0002] Mass spectrometry has been widely used in the fields of environmental detection, clinical analysis, organic synthesis, drug development, protein and metabolomics due to its advantages of high sensitivity, fast analysis speed and strong specificity. The principle of mass spectrometry is to perform mass analysis and structural identification of samples by measuring the mass-to-charge ratio information of sample ions. The structure and composition of protein molecules determine the function of proteins, and the analysis of protein structures is crucial for proteomics, disease diagnosis, drug design, etc. Based on different principles, ion mobility spectrometry (IMS) and tandem mass spectrometry (MSn) are two widely used mass spectrometry techniques for ion struct...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): H01J49/16H01J49/40G01N27/62
CPCH01J49/16H01J49/40G01N27/62G01N27/622
Inventor 徐伟袁涛
Owner 深圳市卓睿通信技术有限公司
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