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A multi-directional light-functionalized instrument for surface modification of titanium alloy internal plants and its application method

A titanium alloy, optical function technology, applied in the directions of bone implants, energy efficiency improvement, process efficiency improvement, etc., can solve the problems of lack of optical functional instruments, inability to illuminate internal holes, and large light source structure, and achieve increased Protein absorption, improved surface structure and performance, and efficient treatment

Active Publication Date: 2022-05-20
BEIJING SURFACE MEDICAL EQUIP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are still many problems that have not been resolved. First, the existing irradiation treatment can only treat the surface of the structure, and cannot treat the inner surface of the porous structure. Second, the existing treatment uses a high-pressure mercury lamp, and the ultraviolet wavelength emitted by it is fixed. , the structure of the light source is bulky, usually used in a fixed position, and can only irradiate the structural parts from one angle, lacking suitable photofunctional instruments. It is necessary to have holes in the interior to facilitate the entry of cells into the colonization and solve the problem of bone fusion after implantation; fourth, the structural pores of 3D printed porous structural parts or porous implants are complex, and existing technical means cannot irradiate irregular internal pores

Method used

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  • A multi-directional light-functionalized instrument for surface modification of titanium alloy internal plants and its application method
  • A multi-directional light-functionalized instrument for surface modification of titanium alloy internal plants and its application method
  • A multi-directional light-functionalized instrument for surface modification of titanium alloy internal plants and its application method

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Experimental program
Comparison scheme
Effect test

preparation example Construction

[0065] Preparation of porous Ti6A4V prosthesis

[0066] The porous titanium alloy stent used in the embodiment of the present invention is prepared by EBM (electron beam melting) rapid prototyping technology, including 3 kinds of specifications for different test and detection respectively: (1) a cylinder with a diameter of 10mm and a height of 5mm , used for cell experiments; (2) A cylinder with a diameter of 5 mm and a height of 6 mm, used for material characterization, in vitro mechanical testing, cell culture, implantation experiments, etc.; (3) EBM technology was used to prepare pictures with a diameter of 10 mm and a thickness of 1 mm Ti6A14V-like material was used for characterization. See Table 1 below.

[0067]

[0068] The prosthesis is designed based on CAD image software (CATIA and INCATUSA), with an internal pore diameter of 640 μm, and a pillar diameter of 400 μm, which is a cylinder with diamond-like lattice pores. After the design is completed, export the ...

Embodiment 1

[0069] Embodiment 1: Structure and parameter design of photofunctionalized instrument

[0070] See attached figure 1 , provides an example of the photofunctionalized irradiation device of the present invention, its parameters satisfy:

[0071] 1) The light source is composed of two groups of wave bands, one group is 365±20nm (365nm is the peak value, hereinafter referred to as the 365nm band), and the other group is 270±20nm (270nm is the peak value, hereinafter referred to as the 270nm band); the light source is an LED light source, which is small in size and convenient Compactly arranged, the ultraviolet wavelength emitted by the light source is usually dominated by a certain wavelength, supplemented by adjacent wavelengths, so only the peak value is used to describe the light source;

[0072] 2) When irradiating, the energy distribution at any position of the cavity: the irradiating energy in the 270nm band is greater than 2mw / cm 2 , 365nm band irradiation energy is great...

Embodiment 2

[0078] Embodiment 2: Using the optical functionalization instrument of the present invention to carry out optical functionalization treatment on titanium alloy materials and experimental detection of treated titanium alloy materials

[0079] 2.1 Experimental grouping and corresponding processing

[0080] The experiment was divided into 5 groups, namely GC (control group), GL, G270, G365 and GU. Among them, GC did not accept light treatment, and GL accepted 15 minutes of ultraviolet high-pressure mercury lamp irradiation; G270, G365 and GU groups were instrument treatment groups of the present invention, which were respectively 270nm, 365nm, 270nm and 365nm dual-wavelength irradiation, and the irradiation time was 15 minutes. minute.

[0081] GC (control group) treatment process: after 4 weeks in a laboratory environment (normal temperature, normal pressure, air environment), place it on a sterile operating table for 15 minutes (without irradiation), and keep it sealed for 24 ...

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Abstract

The present invention provides a multi-directional photofunctionalized instrument for surface modification of titanium alloy internal plants and its use method; the device includes at least two ultraviolet light sources capable of emitting ultraviolet rays, so that the titanium alloy structure located therein can be modified. Further, the ultraviolet light source can also include ultraviolet lamps that emit at least two different wavelengths of ultraviolet rays; this method irradiates from different angles, or uses at least two ultraviolet rays of different wavelengths to treat titanium alloys, which can be used in titanium alloy structures Significant performance improvements were achieved on the surface of the part, as well as on the exterior and interior surfaces of the porous titanium alloy structure.

Description

technical field [0001] The invention belongs to the field of photofunctionalization, and in particular relates to a multi-directional photofunctionalization instrument aimed at modifying the surface of titanium alloy inner plants and a use method thereof. Background technique [0002] Photofunctionalization refers to the technology of modifying the surface of metal implants (especially titanium alloys) by using ultraviolet rays of specific wavelength, intensity, and irradiation time to enhance their physical and chemical properties and biological effects. After the titanium alloy implant is exposed to the environment after fabrication, it will gradually lose its biological activity, which can be reactivated by exposure to ultraviolet light. However, there are still many problems that have not been resolved. First, the existing irradiation treatment can only treat the surface of the structure, and cannot treat the inner surface of the porous structure. Second, the existing tr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/28C22F3/00B22F10/60B22F10/38B33Y40/20
CPCA61F2/28A61F2/30942C22F3/00B22F10/60B22F10/38B33Y40/20A61F2002/3093Y02P10/25
Inventor 刘忠军尹川张腾
Owner BEIJING SURFACE MEDICAL EQUIP CO LTD