A multi-directional light-functionalized instrument for surface modification of titanium alloy internal plants and its application method
A titanium alloy, optical function technology, applied in the directions of bone implants, energy efficiency improvement, process efficiency improvement, etc., can solve the problems of lack of optical functional instruments, inability to illuminate internal holes, and large light source structure, and achieve increased Protein absorption, improved surface structure and performance, and efficient treatment
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[0065] Preparation of porous Ti6A4V prosthesis
[0066] The porous titanium alloy stent used in the embodiment of the present invention is prepared by EBM (electron beam melting) rapid prototyping technology, including 3 kinds of specifications for different test and detection respectively: (1) a cylinder with a diameter of 10mm and a height of 5mm , used for cell experiments; (2) A cylinder with a diameter of 5 mm and a height of 6 mm, used for material characterization, in vitro mechanical testing, cell culture, implantation experiments, etc.; (3) EBM technology was used to prepare pictures with a diameter of 10 mm and a thickness of 1 mm Ti6A14V-like material was used for characterization. See Table 1 below.
[0067]
[0068] The prosthesis is designed based on CAD image software (CATIA and INCATUSA), with an internal pore diameter of 640 μm, and a pillar diameter of 400 μm, which is a cylinder with diamond-like lattice pores. After the design is completed, export the ...
Embodiment 1
[0069] Embodiment 1: Structure and parameter design of photofunctionalized instrument
[0070] See attached figure 1 , provides an example of the photofunctionalized irradiation device of the present invention, its parameters satisfy:
[0071] 1) The light source is composed of two groups of wave bands, one group is 365±20nm (365nm is the peak value, hereinafter referred to as the 365nm band), and the other group is 270±20nm (270nm is the peak value, hereinafter referred to as the 270nm band); the light source is an LED light source, which is small in size and convenient Compactly arranged, the ultraviolet wavelength emitted by the light source is usually dominated by a certain wavelength, supplemented by adjacent wavelengths, so only the peak value is used to describe the light source;
[0072] 2) When irradiating, the energy distribution at any position of the cavity: the irradiating energy in the 270nm band is greater than 2mw / cm 2 , 365nm band irradiation energy is great...
Embodiment 2
[0078] Embodiment 2: Using the optical functionalization instrument of the present invention to carry out optical functionalization treatment on titanium alloy materials and experimental detection of treated titanium alloy materials
[0079] 2.1 Experimental grouping and corresponding processing
[0080] The experiment was divided into 5 groups, namely GC (control group), GL, G270, G365 and GU. Among them, GC did not accept light treatment, and GL accepted 15 minutes of ultraviolet high-pressure mercury lamp irradiation; G270, G365 and GU groups were instrument treatment groups of the present invention, which were respectively 270nm, 365nm, 270nm and 365nm dual-wavelength irradiation, and the irradiation time was 15 minutes. minute.
[0081] GC (control group) treatment process: after 4 weeks in a laboratory environment (normal temperature, normal pressure, air environment), place it on a sterile operating table for 15 minutes (without irradiation), and keep it sealed for 24 ...
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