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Pharmaceutical composition for treating reflux esophagitis and preparation method thereof

A technique for reflux esophagitis and a composition is applied in the directions of drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc., and can solve the problems of high recurrence rate, increased fractures, many side effects, etc., and achieves quick effect and toxicity. Small side effects, easy to use effect

Inactive Publication Date: 2021-09-28
XINJIANG CICONHABO UYGUR MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, proton pump inhibitor (PPI) is the first choice for drug treatment. Although the curative effect is significant, the recurrence rate is high, and long-term use has many side effects, such as increasing the risk of fractures, and simultaneously increasing the risk of Clostridium difficile infection, and Long-term strong acid suppression therapy can cause indigestion, etc.

Method used

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  • Pharmaceutical composition for treating reflux esophagitis and preparation method thereof
  • Pharmaceutical composition for treating reflux esophagitis and preparation method thereof

Examples

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preparation example Construction

[0041]The preparation method of the above-mentioned medicine is as follows: after pulverizing pinnat, cumin, dried ginger, pomegranate seed, Artemisia argyi, octopus, corrugated seed, xanluxiang and cardamom into fine powder, and mixing it with pearl powder to obtain the drug described.

[0042] Preferably, after the cumin is soaked in vinegar for 24 hours, it is dried, fried and then pulverized.

[0043] Further preferably, described vinegar is grape vinegar, and its consumption is 4 times of cumin;

[0044] The temperature of the frying is 80° C., and the time is 20-30 minutes.

[0045] Preferably, the corrugated nuts are calcined until they become crisp, then allowed to cool, and then pulverized.

[0046] Preferably, the fineness of the fine powder is 60-160 mesh

[0047] Further, the preparation method further includes: mixing the fine powder and pearl powder, adding medically acceptable auxiliary materials to make an oral preparation to obtain the medicine.

[0048] U...

Embodiment 1

[0053] Concrete operation steps are as follows: (parts in the embodiment are by weight)

[0054] A Weighing raw materials: Weigh 30-200 parts of Pingna, 16-140 parts of cumin, 22-160 parts of dried ginger, 12-120 parts of pomegranate seeds, 24-180 parts of Artemisia argyi, 10-80 parts of sea octopus, 8-60 parts of corrugated seeds, 3-30 parts of pearl powder, 6-60 parts of incense, and 5-50 parts of cardamom.

[0055] B: Take clean cumin, add 4 times the amount of grape vinegar and soak for 24 hours, take it out and dry it, fry it in an induction cooker at 80°C for about 20-30 minutes, set aside.

[0056] C: Take clean corrugated seeds, put them in a suitable container, calcinate them in a smokeless fire until they are crispy, take them out, let them cool, crush them, and set them aside.

[0057] D: Grind pinnatine, dried ginger, pomegranate seeds, Artemisia argyi, sea octopus, Xunluxiang, cardamom and the above vinegar-made cumin and calcined corrugated seeds into fine powde...

Embodiment 2

[0062] Embodiment 2 (based on 1 part)

[0063] Concrete operation steps are as follows: (parts in the embodiment are by weight)

[0064] A Weighing raw materials: Weighing 15-160 parts of Pingna, 10-90 parts of cumin, 7-70 parts of dried ginger, 8-80 parts of pomegranate seeds, 14-140 parts of Artemisia annua, 8-60 parts of sea octopus, 5-40 parts of corrugated seeds, 4-20 parts of pearl powder, 7-60 parts of smoked Luxiang, 6-40 parts of cardamom.

[0065] B: Take clean cumin, add 4 times the amount of grape vinegar and soak for 24 hours, take it out and dry it, fry it in an induction cooker at 80°C for about 20-30 minutes, set aside.

[0066] C: Take clean corrugated seeds, put them in a suitable container, calcinate them in a smokeless fire until they are crispy, take them out, let them cool, crush them, and set them aside.

[0067] D: Grind pinnatine, dried ginger, pomegranate seeds, Artemisia argyi, sea octopus, Xunluxiang, cardamom and the above vinegar-made cumin and ...

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Abstract

The invention discloses a pharmaceutical composition for treating reflux esophagitis and a preparation method thereof. The pharmaceutical composition for treating reflux esophagitis comprises sodium carbonate, cumin, dried ginger, pomegranate seed, artemisia rupestris, cuttlebone, concha arcae, pearl powder, sweet basil and cardamom. The invention also discloses a preparation method of the pharmaceutical composition. The pharmaceutical composition for treating reflux esophagitis is prepared from traditional Chinese medicines, has the effects of warming stomach and dispelling cold, refreshing brain and soothing nerves, relieving hyperacidity and stopping pain, and astringing and eliminating swelling, and can be used for treating symptoms such as heartburn, sour regurgitation, chest pain, gastrectasia, belching and nausea caused by reflux esophagitis.

Description

technical field [0001] The invention specifically relates to a pharmaceutical composition for treating reflux esophagitis and a preparation method thereof. Background technique [0002] Reflux esophagitis (RE) refers to a disease of reflux-related symptoms, esophagitis and / or complications caused by the reflux of gastric contents into the esophagus, which belongs to Gastro-esophageal reflux disease , GERD) category. In western countries, the incidence rate of GERD is 10-30%, and in Asia, the incidence rate is generally 5-10%. The detection rate of GERD also tends to increase gradually, and its incidence rate is about 6% according to epidemiological surveys in Beijing, Shanghai, and Guangzhou; the investigation of the Endoscopy Department of People's Hospital of Xinjiang Autonomous Region found that the incidence rate of GERD symptoms reached 35%. Related reports have shown that reflux esophagitis can be complicated by Barrett's esophagus, which is a precancerous lesion of ...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P1/04A61K35/618
CPCA61K36/534A61K36/23A61K36/9068A61K36/185A61K36/28A61K35/618A61K36/22A61K36/9064A61P1/04A61K2300/00
Inventor 陈金成
Owner XINJIANG CICONHABO UYGUR MEDICINE
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