Biomarker for diagnosing cerebral infarction of white matter lesion patient and application of biomarker

A biomarker, cerebral infarction technology, applied in disease diagnosis, biological testing, biomaterial analysis, etc., can solve the problems of moving patients, high cost, unfavorable patient treatment and recovery, etc.
CN113447599AActive Publication Date: 2021-09-28BAO FENG BIOTECH (BEIJING) CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
BAO FENG BIOTECH (BEIJING) CO LTD
Publication Date
2021-09-28

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Abstract

The invention provides application of a biomarker phosphatidylinositol (22: 0 / 19: 0) in preparation of a detection reagent for diagnosing cerebral infarction of a white matter lesion patient. The risk of cerebral infarction of the white matter lesion patient is judged by combining the biomarker lipophosphatidylinositol (22: 0 / 19: 0) with glucosylceramide (d18: 0 / 24: 1 (15Z)), beta-hydroxyethyl ethanolamine, tomatidine, phosphatidylserine (22: 6 / 20: 1) or decanoyl carnitine. Cerebral infarction can be prevented in advance.
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Description

technical field

[0001] The invention belongs to the technical field of biological detection, and in particular relates to a biomarker for diagnosing cerebral infarction in patients with leukoencephalopathy and its application. Background technique

[0002] With the aging of society, the incidence of stroke has increased sharply, and the incidence of stroke in our country is higher than the international average level. Among them, ischemic stroke (cerebral infarction) is caused by the stenosis or occlusion of cerebral arteries resulting in the loss of brain tissue. Blood necrosis accounts for more than 70% of all strokes. White matter lesion (WML) is a common neurodegenerative disease, the most typical pathological manifestations are damage to the integrity of white matter or demyelination, which is common in stroke, Parkinson's disease, Alzheimer's disease Alzheimer's disease, multiple sclerosis, schizophrenia and many other diseases. The typical response of white matter t...

Claims

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