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2 results about "GLYCOCERAMIDES" patented technology

Variants of beta-glucocerebrosidase for use in treating Gaucher Disease

PendingAU2021245409B2DiseaseCerebroside
A genetically modified human beta-glucocerebrosidase (GCase) is disclosed. The genetically modified GCase comprising an amino acid sequence at least 85 % identical to SEQ ID NO: 2; and comprising mutations at coordinates L34P, K224N / G, T369E and N370D, where the coordinates correspond to said SEQ ID NO: 2; and capable of catalyzing hydrolysis of a glycolipid glucosylceramide (GlcCer). Pharmaceutical compositions comprising the genetically modified GCase and therapeutic methods of using same are also disclosed.
Owner:YEDA RES & DEV CO LTD

Vacuum ice-sculpture strawberry cell liquid skin care agent, its preparation method and application in skin moisturizing repair

PendingCN122320852Aincrease moisture contentOptimized formulaBiotechnologyCellulose
This invention discloses a vacuum-extracted strawberry cell sap skincare agent, its preparation method, and its application in skin moisturizing and repair, belonging to the field of skin care technology. The vacuum-extracted strawberry cell sap skincare agent comprises the following components in parts by weight: 70-85 parts strawberry cell sap, 0.1-0.5 parts sodium polyglutamate, 0.1-1 parts trehalose, 0.05-0.3 parts ceramide, 0.1-0.3 parts propylene glycol, 2-10 parts glycerin, 0.1-0.5 parts sodium hyaluronate, 0.2-0.8 parts hydroxyethyl cellulose, and 0.1-0.5 parts xanthan gum. This invention is the first to use strawberry cell sap as the core active ingredient in a skincare product, breaking through the limitations of traditional strawberry extract applications and fully exploring the skincare potential of natural molecules, water-soluble antioxidants, and fruit acids in the cell sap. Through the scientific formulation of sodium polyglutamate, trehalose, ceramide, and other ingredients, the moisturizing, repairing, and barrier-strengthening functions of the cell sap are significantly enhanced.
Owner:RIZHAO CHANGRONG BIOTECHNOLOGY CO LTD +1