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Compound oral care solution and preparation method thereof

An oral care solution and compound technology, applied in the field of oral care, can solve problems such as compound oral care drugs that have not yet been seen, and achieve the effects of avoiding the formation of dental plaque and calculus, preventing colonization, and preventing colonization.

Active Publication Date: 2021-12-07
TROPICAL CORP STRAIN RESOURCE INST CHINESE ACAD OF TROPICAL AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no report on the compound oral care medicine composed of Aina sesame oil, nude flower purple pearl extract and nootropic oil

Method used

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  • Compound oral care solution and preparation method thereof
  • Compound oral care solution and preparation method thereof
  • Compound oral care solution and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A compound oral care solution, comprising the following raw materials in parts by weight: 0.25 parts of Aina sesame oil, 0.2 parts of Nadihuazizhu extract, 0.1 parts of nootropic oil, 10 parts of glycerin, 5 parts of ethanol, 2.5 parts of sorbitol, Tween-20 1.5 parts, citric acid 0.01 parts, saccharin sodium 0.3 parts, peppermint oil 0.3 parts, lemon essence 0.2 parts, water 30 parts.

Embodiment 2

[0032] A compound oral care solution, comprising the following raw materials in parts by weight: 0.15 parts of Aina sesame oil, 0.2 parts of Nadihuazizhu extract, 0.05 parts of nootropic oil, 10 parts of glycerin, 3 parts of ethanol, 2 parts of sorbitol, 1 part of Tween-20, 0.01 part of citric acid, 0.2 part of sodium saccharin, 0.25 part of peppermint oil, 0.1 part of essence, 20 parts of water.

Embodiment 3

[0034] A compound oral care solution, comprising the following raw materials in parts by weight: 0.15-0.3 parts of Aina sesame oil, 0.3 parts of Nadihuazizhu extract, 0.1 part of nootropic oil, 5 parts of glycerin, 6 parts of ethanol, and 5 parts of sorbitol 2 parts of Tween-20, 0.02 parts of citric acid, 0.35 parts of sodium saccharin, 0.35 parts of peppermint oil, 0.3 parts of essence, and 50 parts of water.

[0035] The preparation method of the described compound oral care liquid of embodiment 1-3, comprises the following steps:

[0036] (1) Add sodium saccharin, glycerin, sorbitol, Tween-20, and citric acid into water at 50°C, mix and cool down to 40°C to obtain the first oral care solution;

[0037] (2) dissolving the ethanol solution that is 75% by the Eina sesame oil with mass fraction to make Aina sesame oil alcohol solution;

[0038] (3) In the first oral care solution, add Aina sesame oil alcohol solution, nude flower purple pearl extract, nootropic oil, peppermint...

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PUM

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Abstract

The invention discloses a compound oral care solution. The compound oral care solution is prepared from the following raw materials in parts by weight: 0.15 to 0.3 part of blumea balsamifera oil, 0.2 to 0.3 part of callicarpa nudiflora extract, 0.05 to 0.1 part of alpinia oxyphylla oil, 10 to 15 parts of glycerol, 3 to 6 parts of ethanol, 2 to 5 parts of sorbitol, 1 to 2 parts of tween-20, 0.01 to 0.02 part of citric acid, 0.2 to 0.35 part of saccharin sodium salt, 0.25 to 0.35 part of peppermint oil, 0.1 to 0.3 part of essence and 20 to 50 parts of water. The invention further discloses a preparation method of the compound oral care solution. According to the compound oral care solution and the preparation method thereof, the compound oral care solution is highly sensitive to staphylococcus aureus, candida albicans and streptococcus mutans, is sensitive to escherichia coli and porphyromonas gingivalis, and can well prevent colonization of oral pathogenic bacteria on a dental acquired membrane, thereby avoiding formation of dental plaque and dental calculus.

Description

technical field [0001] The invention relates to the field of oral care, in particular to a compound oral care solution and a preparation method thereof. Background technique [0002] Dental acquired film is a thin film layer of salivary protein attached to the tooth surface within a few minutes after the tooth is professionally cleaned. Oral bacteria attach to the formed tooth-acquired membrane through specific molecular interactions, forming the initial form of bacterial biofilm; it shows that tooth-acquired membrane (early oral biofilm) provides a suitable living environment for oral pathogenic bacteria. Bacteria colonized on biofilms include streptococci, gram-positive bacilli, gram-negative bacilli, etc. Streptococci were still the main adsorbents in the early biofilms, and filamentous bacteria, rod-shaped bacteria, actinomycetes and Veillonella, etc. are adsorbed on the acquired film, and finally the bacterial biofilm gradually forms a plaque biofilm, and the maturatio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9062A61K47/12A61K47/22A61K47/26A61K47/44A61P1/02A61P31/04A61P31/10A61K36/28A61K36/85
CPCA61K36/28A61K36/85A61K36/9062A61K47/44A61K47/26A61K47/12A61K47/22A61P1/02A61P31/04A61P31/10A61K2236/19A61K2236/331A61K2236/55A61K2236/51A61K2300/00Y02A50/30
Inventor 谢小丽于福来王丹陈振夏王凯胡璇官玲亮黄梅
Owner TROPICAL CORP STRAIN RESOURCE INST CHINESE ACAD OF TROPICAL AGRI SCI
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