Preparation method of broussonetia papyrifera oral preparation for clearing heat, enhancing immunity and improving intestinal functions

A technology of intestinal function and oral preparations, applied in the field of biomedicine, can solve problems such as poor development of medicinal value, lack of effective product support, use of mulberry trees and industrial development, etc., to increase water solubility Sexual efficiency, improvement of intestinal function, and low production cost

Pending Publication Date: 2021-12-17
WEST ANHUI UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, from the perspective of current industrial development, the use and industrialization of mulberry only stays in the field of feed, and its medicinal value has not been well developed.
Especially in the field of biomedicine, there is a lack of effective product support

Method used

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  • Preparation method of broussonetia papyrifera oral preparation for clearing heat, enhancing immunity and improving intestinal functions
  • Preparation method of broussonetia papyrifera oral preparation for clearing heat, enhancing immunity and improving intestinal functions
  • Preparation method of broussonetia papyrifera oral preparation for clearing heat, enhancing immunity and improving intestinal functions

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] A preparation method of mulberry oral preparation for clearing away heat, increasing immunity and improving intestinal function, comprising the following steps:

[0039] (1) Take 5 parts of mulberry superfine powder by weight, add 10 parts of petroleum ether for extraction, filter to obtain filter residue a; after filter residue a is dried, add 5 parts of dichloromethane for extraction, filter to obtain filter residue b; filter residue b After drying, add 5 parts of ethyl acetate for extraction and filter to obtain filter residue c; after drying filter residue c, add 5 parts of n-butanol for extraction and filter to obtain filter residue d; after drying filter residue d, add 30 parts The water is condensed and refluxed for extraction to obtain extract A;

[0040] (2) After centrifuging the extract A, vacuum negative pressure filtration, collecting the filtrate, and conducting electrothermal negative pressure drying to constant weight at 30°C, to obtain the solid powder ...

Embodiment 2

[0048] A preparation method of mulberry oral preparation for clearing away heat, increasing immunity and improving intestinal function, comprising the following steps:

[0049] (1) Take 10 parts of mulberry superfine powder by weight, add 20 parts of petroleum ether for extraction, filter to obtain filter residue a; after filter residue a is dried, add 15 parts of dichloromethane for extraction, filter to obtain filter residue b; filter residue b After drying, add 10 parts of ethyl acetate for extraction and filter to obtain filter residue c; after drying filter residue c, add 10 parts of n-butanol for extraction and filter to obtain filter residue d; after drying filter residue d, add 40 parts The water is condensed and refluxed for extraction to obtain extract A;

[0050] (2) After centrifuging the extract A, vacuum negative pressure filtration, collect the filtrate, and conduct electrothermal negative pressure drying at 50°C to a constant weight to obtain the solid powder B...

Embodiment 3

[0058] A preparation method of mulberry oral preparation for clearing away heat, increasing immunity and improving intestinal function, comprising the following steps:

[0059] (1) Take 15 parts of mulberry superfine powder by weight, add 30 parts of petroleum ether for extraction, filter to obtain filter residue a; after filter residue a is dried, add 20 parts of dichloromethane for extraction, filter to obtain filter residue b; filter residue b After drying, add 15 parts of ethyl acetate for extraction and filter to obtain filter residue c; after drying filter residue c, add 15 parts of n-butanol for extraction and filter to obtain filter residue d; after drying filter residue d, add 50 parts The water is condensed and refluxed for extraction to obtain extract A;

[0060] (2) After centrifuging the extract A, vacuum negative pressure filtration, collect the filtrate, and conduct electrothermal negative pressure drying at 60°C to constant weight to obtain the mulberry solid p...

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Abstract

The invention discloses a preparation method of a broussonetia papyrifera oral preparation for clearing heat, enhancing immunity and improving intestinal functions and belongs to the technical field of biomedicines. According to the method, broussonetia papyrifera leaves are used as a raw material, components with relatively low polarity are removed through solvents such as petroleum ether, dichloromethane, ethyl acetate and n-butyl alcohol, components with relatively high polarity are reserved, finally extraction is conducted through water with relatively high polarity, an immunological enhancement beneficial component is obtained, deep processing is conducted through a preparation technology, and the broussonetia papyrifera oral preparation for clearing heat, enhancing immunity and improving the intestinal functions is obtained; and experiments prove that the broussonetia papyrifera oral preparation has the effects of clearing heat, enhancing immunity, promoting growth and regulating the steady state of intestinal florae.

Description

technical field [0001] The invention relates to the technical field of biomedicine, and more specifically relates to a preparation method of a mulberry oral preparation for clearing away heat, increasing immunity and improving intestinal function. Background technique [0002] The leaves of the tree have the effects of clearing heat, cooling blood, promoting dampness, and killing insects. They are often used to treat enteritis, dysentery, and epistaxis, and have important medicinal value. In addition, the mulberry tree has a large planting area and a wide coverage, and has strong resource and policy advantages. [0003] However, from the perspective of current industry development, the use and industrialization of mulberry only stays in the field of feed, and its medicinal value has not been well developed. Especially in the field of biomedicine, there is a lack of effective product support. [0004] The immune system is an important guarantee for humans and animals to fig...

Claims

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Application Information

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IPC IPC(8): A61K36/60A61K9/00A61P29/00A61P37/04A61P1/00A23L33/105A61K127/00
CPCA61K36/60A61K9/0053A61K47/26A61P29/00A61P37/04A61P1/00A23L33/105A61K2236/35A61K2236/33A61K2236/39A61K2236/51A61K2236/53A23V2002/00A23V2200/30A23V2200/324A23V2200/32A23V2250/21A23V2250/61A23V2250/606A23V2250/708A23V2300/46
Inventor 蒋平左瑞华徐光沛何燕飞王敬利
Owner WEST ANHUI UNIV
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