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Prebiotic toothpaste and application thereof

A prebiotic and toothpaste technology, applied in dentistry, cosmetic preparations, medical science, etc., can solve the problems of different composition and inactivity of oral flora, and achieve the effect of microbial ecological prevention or treatment

Pending Publication Date: 2022-03-01
量子高科(广东)生物有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Each person's oral flora is different, and it is unknown whether different microorganisms can play their due role in different environments. Therefore, the prebiotics added to the prebiotic toothpaste currently on the market may not be suitable for everyone's oral environment , so whether prebiotics can exert their ideal effect also varies from person to person
In addition, most of the prebiotics in the existing prebiotic toothpaste are inactive dead bacteria, so there are doubts about their efficacy

Method used

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  • Prebiotic toothpaste and application thereof
  • Prebiotic toothpaste and application thereof
  • Prebiotic toothpaste and application thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0040] Among them, the preparation method of the oligofan reagent includes the following steps:

[0041] (1) Preparation of sucrose solution: In the addition of sucrose, water, add water, stir up to sucrose is completely dissolved, wherein the mass percentage of sucrose is 22-65% in sucrose and water; then uses the mixture Diatomal coil filter filter, sucrose solution;

[0042] (2) Transformation: In the input of the sucrose solution, the temperature of the conversion tank is 32-55 ° C, and the pH of the sucrose solution is 4.8-7.8, and then the sucrose solution is input to the reactive column of the fixed enzyme, The sucrose solution was subjected to the upper and back out, refluxed into the conversion tank; transformed 12-48 hours, detecting the low polyggate content to stop transformation, and syrup;

[0043] (3) Isolation and purification: Sterilization of the syrup for 15-20 seconds at 121-125 ° C, desalting the syrup with the ion exchange resin, the control conductivity is b...

Embodiment 1

[0048] The invention is composed of the following components: oligodose reagent 2.5%, sorbitol 55%, glycerol 5%, polyethylene glycol 3%, sodium carboxymethylcellulose 0.4%, carolate 0.4%, Normal friction type silica 10%, thickening silica 8%, sodium sodium sodium sodium sodium, 0.3% sodium benzoate, 1.5% sodium dodecyl sulfonate, 1% 香 精;, water; In the fructose reagent, the oligo fruit content is 96.0%, and the content of suck fruit triposugate is 60.0%.

Embodiment 2

[0050] The present invention has been composed of 1% of the following components: oligodose reagents, 55% sorbitol, 5% glycerol, 3% of polyethylene glycol, 0.4% carboxymethylcellulose sodium carboxymethylcellulose, 0.4% kale gelatin, Normal friction type silica 10%, thickening silica 8%, 0.2% sodium glycine, 0.3% sodium benzoate, 1.5% sodium dodecyl sulfonate, 1% mint fragrance, water 14.2%; In the fructose reagent, the oligo fruit content is 96.0%, and the content of suck fruit triposugate is 60.0%.

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Abstract

The invention discloses prebiotic toothpaste, which belongs to the technical field of medical health, and comprises a fructo-oligosaccharide reagent, a humectant, an adhesive, a friction agent, a sweetening agent, a foaming agent and water. The mass percentage of fructo-oligosaccharide in the fructo-oligosaccharide reagent is greater than or equal to 95%, and the mass percentage of kestose in the fructo-oligosaccharide is greater than or equal to 60%; the preparation method of the fructo-oligosaccharide reagent comprises the following steps: converting a prepared sucrose solution serving as a raw material into fructo-oligosaccharide syrup through a biological enzyme method, then desalting and decoloring the syrup, then performing chromatographic separation and purification twice, and finally concentrating and drying the purified substance to obtain the fructo-oligosaccharide reagent. According to the technical scheme, the fructooligosaccharide reagent with the high content of fructooligosaccharide is provided, the content of kestose in fructooligosaccharide is high, the effect of fructooligosaccharide can be achieved more quickly and effectively, and therefore the effects of adjusting the microbial ecology in the oral cavity and further preventing or treating oral diseases are achieved.

Description

Technical field [0001] The present invention belongs to the field of medicine and health, and in particular, the present invention relates to a probiotic imbalance and its application thereof. Background technique [0002] With the advancement of research techniques, many oral diseases such as dental caries, periodontitis, bad breath are found to be related to microorganisms in the oral cavity, especially some pathogenic microorganisms, not only lead to oral disease, but also causing some Physical disease. However, microorganisms in the mouth are not all harmful bacteria, most of which are still a normal flora, these bacteria can promote nutrient absorption, and can also inhibit the progression of hazardous bacteria and reduce the occurrence of oral diseases. [0003] Each person's oral flora is different, and the different microorganisms can have the effects in different environments, and therefore, the probiotics added to the probiotics in the market are not necessarily suitabl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/60A61Q11/00A61P1/02A61P31/02A61P31/04
CPCA61K8/60A61Q11/00A61P1/02A61P31/02A61P31/04Y02A50/30
Inventor 王炜宏杨新球曾宪维魏远安陈子健王涛
Owner 量子高科(广东)生物有限公司