High-activity collagen filler as well as preparation method and application thereof

Abstract

The invention discloses a high-activity collagen filler as well as a preparation method and application thereof, and the preparation method comprises the following steps: step (1): dissolving leather shavings and an alkalized substance buffer agent in water, degrading, cooling, adding protease and ethanol, filtering, and drying in vacuum to obtain collagen / potassium carbonate powder; (2) dissolving palladium acetate, potassium carbonate and 2-dicyclohexylphosphine-2 ', 4', 6 '-triisopropylbiphenyl in tert-butyl alcohol, introducing nitrogen, mixing, and discharging excess air to prepare a catalyst solution; (3) dissolving the catalyst solution, collagen / potassium carbonate powder, potassium carbonate, triethylamine and methanol 4-bromobenzaldehyde dimethyl acetal in tert-butyl alcohol, introducing nitrogen for reaction, cooling, carrying out reduced pressure distillation to remove the tert-butyl alcohol solvent, and adding water to obtain high-activity collagen filler; the particle size of the high-activity collagen filler is 300-800 nm, the particle size distribution coefficient is 0.150-0.350, the high-activity collagen filler has certain amphoteric property, the zeta potential is-20--40 mV, and the content of water insoluble substances is smaller than or equal to 3%.

Description

technical field [0001] The invention relates to the technical field of tanning, in particular to a high-activity collagen filler and a preparation method and application thereof. Background technique [0002] The style of leather and leather products is constantly changing with the improvement of people's consumption level. In recent years, the style of leather and leather products has gradually shifted from "plastic" to "sensual". "Plastic feeling" is mainly reflected by the large molecular acrylic resin retanning agent and small and medium molecular acrylic resin retanning agent. At the same time, a small amount of polyurethane resin will be introduced in the retanning filling process to improve the uniformity. Relatively speaking, the plastic feeling is relatively strong. Heavy leather uniformity is good. In recent years, consumers are more advocating the feeling of natural leather, that is, sensuality. The sensuality is mainly reflected by protein fillers, and at the s...

AI Technical Summary

Problems solved by technology

[0004] This application provides a high activity collagen filler and its preparation method and application, which solves the problem that the protein filler in the prior art has a large molecular weight, which will reduce the ability of the protein filler to combine with skin collagen fibers. At the same time, the amino group and carboxyl group, The chemical bonds between the active functional groups on the long chain of collagen are mainly hydrogen bonds, and technical problems such as weak adsorption have achieved a high-activity collagen filler with excellent performance, which will not interact with itself The reaction will not cause the molecular weight of the protein filler to be too large, block the gap between the collagen fibers of the skin, cause stuck surfaces, and affect the absorption of other materials in the follow-up; at the same time, it also reduces the use of highly active collagen fillers and tannins

Images