High-activity bone construction method based on bone marrow suction enrichment system

Abstract

The invention belongs to the technical field of bone tissue engineering, and particularly relates to a high-activity bone construction method based on a bone marrow suction enrichment system, which comprises the following steps: soaking an allogeneic bone decalcification scaffold in a prepared peptide solution, and flushing after soaking to obtain a self-assembled polypeptide modified allogeneic bone decalcification scaffold; putting the prepared enrichment material into an inner tank body of a material mixing and stirring tank of a bone marrow suction enrichment system, and enriching according to preset time; and after the enrichment is completed, discharging the waste liquid in the material mixing and stirring tank to obtain the constructed high-activity bone repair material. The problems that in the prior art, the bone taking mode is not accurate, and bone forming materials are prone to losing can be solved.

Description

technical field [0001] The invention belongs to the technical field of bone tissue engineering, and in particular relates to a highly active bone construction method based on a bone marrow aspiration enrichment system. Background technique [0002] At present, with the rapid development of the medical industry, technologies in various fields of medical care are also developing rapidly, and a variety of new medical technologies have emerged, but there are also some defects. Among them, the repair technology of bone injury and bone defect is a major orthopedic problem. At present, the way to solve bone injury and bone defect is bone grafting. In the bone grafting method, the method to solve the lack of bone at the planting site is to use autologous bone, allogeneic bone, xenograft bone and artificial bone for transplantation; autologous bone transplantation has the advantages of Good histocompatibility, osteoconductivity, osteoinductivity, and non-immunogenicity have become t...

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Problems solved by technology

[0004] The technical problem to be solved by the present invention is to provide a highly active bone construction method based on a bone marrow aspiration enrichment system to solve the problems of inaccurate bone extraction methods and easy loss of osteogenic materials in the prior art

[0006] The principle and advantages of the basic scheme 1 provided by the present invention: in the existing related technology, the bone extraction equipment such as osteotome and bone digging spoon is combined with repeated physical percussion to separate the bone, and the bone extraction is inaccurate and easy to damage the peripheral blood vessels and nerves. And there is a problem of loss of a large amount of autologous bone material during the bone harvesting process

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