High-strength self-recoverable multifunctional conductive hydrogel with temperature/pH dual response as well as preparation method and application of high-strength self-recoverable multifunctional conductive hydrogel

Abstract

The invention relates to high-strength self-restorable conductive hydrogel with temperature / pH dual response as well as a preparation method and application thereof. The hydrogel is prepared by dissolving a comonomer A, a comonomer B, a biomacromolecule C, a chemical cross-linking agent D and a physical cross-linking agent E in water and then polymerizing. The hydrogel prepared by the invention not only has temperature sensitive characteristics and pH sensitive characteristics, but also has relatively high strength and tensile rate, can be circularly stretched, and can be self-recovered and even self-enhanced. Besides, the hydrogel disclosed by the invention also has electrical conductivity, and the electrical conductivity of the hydrogel can be changed along with the change of the temperature, the stretching ratio and the environmental pH value, so that the electrical conductivity of the hydrogel has multiple sensitivities, and in addition, the hydrogel also has universal adhesion. Based on the attributes, the hydrogel is expected to be applied to a plurality of biomedical fields such as biosensors, wearable electronic skin, soft tissue engineering, drug controlled release and the like.

Description

technical field

[0001] The invention relates to a conductive hydrogel, in particular to a high-strength, self-recoverable multifunctional conductive hydrogel with dual response to temperature / pH, and a preparation method and application thereof. Background technique

[0002] In recent years, conductive hydrogels have received extensive exploration and attention due to their great application potential in many fields such as electronic skin, bioelectronic sensors, and tissue engineering. With the advancement and deepening of research and application, single-functional conductive hydrogels can no longer meet the actual needs of many biomedical fields. For example, the field of bionic electronic skin not only requires hydrogels to have good mechanical properties, but also requires conductive hydrogels to respond to changes in the external environment, and also requires conductive hydrogels to undergo volume changes and electrical signal changes under stimulation. Furthermore, ...

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