Antioxidant effusion clearing liquid for children and preparation method of antioxidative effusion clearing liquid

An anti-oxidation and children's technology, which is applied in the direction of medical preparations containing active ingredients, anti-toxins, pharmaceutical formulas, etc., can solve the problems of optimization, improvement and deterioration of the anti-oxidation performance of traditional Chinese medicine extracts, and achieve good cleaning performance, no side effects, quick results

Pending Publication Date: 2022-06-07
新绛县兵锁儿科医院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

None of the above patents has optimized and improved the anti-oxidation properties of Chinese medicine extracts, and deterioration problems caused by oxidation may occur in actual production

Method used

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  • Antioxidant effusion clearing liquid for children and preparation method of antioxidative effusion clearing liquid
  • Antioxidant effusion clearing liquid for children and preparation method of antioxidative effusion clearing liquid

Examples

Experimental program
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Effect test

Embodiment 1

[0066] A preparation method of antioxidative children's clearing fluid, comprising the following steps:

[0067] S1: Add 12g hemp seed, 12g jujube, 12g rehmannia glutinosa, 12g large belly skin, 12g scrophularia, 12g licorice, 12g aurantium, 12g fried radish, 12g magnolia, 7g melon seed, 7g atractylodes, 7g ginger Mix and grind into powder, pass through a 10-mesh sieve, and mix to obtain a mixture of Chinese medicinal materials;

[0068] S2: Mix and soak the Chinese medicinal material mixture obtained in step S1 with 30 times the mass of water to obtain a mixed solution, add cellulase, heat at 40°C for 2 hours, then heat up to 90°C for 10 minutes to inactivate the enzyme, filter to remove the medicinal residue, and obtain the Chinese medicinal material extraction liquid; the mass ratio of the Chinese medicinal material mixture to cellulase is 150:1;

[0069] S3: adding physiological saline to the Chinese herbal medicine extract obtained in step S2, fully mixing, adding a co-s...

Embodiment 2

[0071] A preparation method of antioxidative children's clearing fluid, comprising the following steps:

[0072] S1: Add 12g hemp seed, 12g jujube, 12g rehmannia glutinosa, 12g large belly skin, 12g scrophularia, 12g licorice, 12g aurantium, 12g fried radish, 12g magnolia, 7g melon seed, 7g atractylodes, 7g ginger Mix and grind into powder, pass through a 10-mesh sieve, and mix to obtain a mixture of Chinese medicinal materials;

[0073] S2: Mix and soak the Chinese medicinal material mixture obtained in step S1 with 30 times the mass of water to obtain a mixed solution, add cellulase, heat at 40°C for 2 hours, then heat up to 90°C for 10 minutes to inactivate the enzyme, filter to remove the medicinal residue, and obtain the Chinese medicinal material extraction liquid; the mass ratio of the Chinese medicinal material mixture to cellulase is 150:1;

[0074] S3: adding physiological saline to the Chinese herbal medicine extract obtained in step S2, fully mixing, adding a co-s...

Embodiment 3

[0076] A preparation method of antioxidative children's clearing fluid, comprising the following steps:

[0077] S1: Add 12g hemp seed, 12g jujube, 12g rehmannia glutinosa, 12g large belly skin, 12g scrophularia, 12g licorice, 12g aurantium, 12g fried radish, 12g magnolia, 7g melon seed, 7g atractylodes, 7g ginger Mix and grind into powder, pass through a 10-mesh sieve, and mix to obtain a mixture of Chinese medicinal materials;

[0078] S2: Mix and soak the Chinese medicinal material mixture obtained in step S1 with 30 times the mass of water to obtain a mixed solution, add cellulase, heat at 40°C for 2 hours, then heat up to 90°C for 10 minutes to inactivate the enzyme, filter to remove the medicinal residue, and obtain the Chinese medicinal material extraction liquid; the mass ratio of the Chinese medicinal material mixture to cellulase is 150:1;

[0079] S3: adding physiological saline to the Chinese herbal medicine extract obtained in step S2, fully mixing, adding a co-s...

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Abstract

The invention discloses an anti-oxidation effusion clearing liquid for children and a preparation method of the anti-oxidation effusion clearing liquid. The effusion clearing liquid is prepared from the following raw materials in parts by mass: 10 to 15 parts of fructus cannabis, 10 to 15 parts of fructus ziziphi jujubae, 10 to 15 parts of radix rehmanniae recen, 10 to 15 parts of pericarpium arecae, 10 to 15 parts of radix scrophulariae, 10 to 15 parts of liquorice root, 10 to 15 parts of fructus aurantii immaturus, 10 to 15 parts of fried semen raphani, 10 to 15 parts of cortex magnoliae officinalis, 5 to 10 parts of semen trichosanthis, 5 to 10 parts of rhizoma atractylodis macrocephalae and 5 to 10 parts of rhizoma zingiberis recens. According to the preparation method disclosed by the invention, the traditional Chinese medicinal material extracting solution is treated by using enzyme, 4, 3, 5-trihydroxy resveratrol is added in the preparation process of the traditional Chinese medicinal material extracting solution, and the 4, 3, 5-trihydroxy resveratrol can inhibit the combination of protein and lipid and delay the reaction process of protein carbonylation, so that the technical problem of oxidative deterioration of the traditional Chinese medicinal material extracting solution is solved.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to an anti-oxidative children's clearing fluid and a preparation method thereof. Background technique [0002] Rectal administration is a method of administration in which the drug is delivered into the rectum through the anus and quickly enters the blood circulation through the intestinal mucosa, so that the drug exerts a local or systemic therapeutic effect. It is divided into retention enema, rectal drip, and suppository insertion . The rectal mucosa has a special annular structure, the pH of the rectal fluid is 6.8-7.3, and the environment is mild. Compared with oral administration, rectal administration can avoid the influence of unpleasant odor of the drug and the stimulating effect on gastric mucosa, reduce the liver first-pass effect, and improve bioavailability; compared with injection administration, rectal administration is safer . [...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068
CPCA61K36/60A61K36/725A61K36/804A61K36/889A61K36/808A61K36/484A61K36/752A61K36/31A61K36/575A61K36/428A61K36/284A61K36/9068A61K9/0031A61P1/14A61P1/10A61P39/06A61K2236/19A61K2300/00Y02A50/30
Inventor 李兵锁李林红李杨李怡阳李浩杰孙怡路燕天赐李泽恩辉燕密纳李梦茹李哲
Owner 新绛县兵锁儿科医院有限公司
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