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Pipeline uniform stretching device and stretching method for micro-fluidic liquid drop generation

A technology of droplet generation and stretching device, applied in the field of microfluidics, can solve the problems of high price, insufficient uniformity of pipes, and difficulty in achieving microfluidic effect, etc., and achieve the effect of improving the uniformity of stretching

Pending Publication Date: 2022-07-22
广东省科学院生物与医学工程研究所
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  • Abstract
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  • Claims
  • Application Information

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Problems solved by technology

[0003] In the production process of micro-pipes, to achieve the inner diameter of micro-droplets, the pipe needs to be stretched to reduce the inner diameter of the pipe. Today, the pipe is mainly stretched by a hot press and pressure control, and the structure is complex. , the price is expensive, and the uniformity of the stretched pipe is not enough, it is difficult to achieve a good microfluidic effect

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Embodiment Construction

[0032] In order to make those skilled in the art better understand the solutions of the present application, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present application. Obviously, the described embodiments are only The embodiments are part of the present application, but not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative work shall fall within the scope of protection of the present application.

[0033] The terms "first", "second", "third" and "fourth" in the description and claims of the present application and the drawings are used to distinguish different objects, rather than to describe a specific order . Furthermore, the terms "comprising" and "having" and any variations thereof are intended to cover non-exclusi...

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Abstract

The invention discloses a pipeline uniform stretching device and stretching method for micro-fluidic droplet generation, and the device is provided with a pulley assembly, a motor module, a heating assembly comprising a heating element and a heating stretching die, and a control module, and a polymer pipeline is arranged in the heating stretching die; one end of the polymer pipeline is fixed to the pulley assembly, the other end of the polymer pipeline penetrates through the heating and stretching die to be fixed to the motor module, the heating element is controlled to heat the heating and stretching die, and the motor module is controlled to stretch the polymer pipeline. The structure is simple, so that the cost is reduced, the heating element surrounds the heating and stretching die, so that the heating and stretching die and the polymer pipeline can be uniformly heated, meanwhile, the polymer pipeline is finer and more uniform after being stretched under the extrusion force in the heating and stretching die, the stretching uniformity is favorably improved, and the production efficiency is improved. The method can be widely applied to the technical field of microfluidics.

Description

technical field [0001] The invention relates to the field of microfluidics, in particular to a pipe uniform stretching device and a stretching method for the generation of microfluidic droplets. Background technique [0002] Microfluidics refers to the science and technology involved in systems that use micropipes (tens to hundreds of microns in size) to process or manipulate tiny fluids (volumes ranging from nanoliters to picoliters). , emerging interdisciplinary fields of fluid physics, microelectronics, new materials, biology and biomedical engineering. Because of the characteristics of miniaturization and integration, microfluidic devices are often referred to as microfluidic chips, also known as Lab on a Chip and micro-Total Analytical System. Droplet digital PCR needs to separate a small amount of sample into a large number of independent and uniform micro-reaction units for amplification, and perform fluorescence detection on the amplified sample to achieve quantitat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00B81C1/00
CPCB01L3/502707B81C1/00531
Inventor 吴文明郭昱王康宁
Owner 广东省科学院生物与医学工程研究所
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