Composition for maintaining and/or improving memory/learning ability, and food, drug, and feed containing said composition

A technology of learning ability and composition, which is applied in the field of food and drink, can solve the problems of decline, memory and learning ability of microorganisms that have not yet been clarified, and achieve the effect of improving the quality of life, memory and learning ability of decline

Pending Publication Date: 2022-07-22
SNOW BRAND MILK PROD CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, the role of microbes in the decline in memory and learning that occurs with aging (aging) has not been elucidated

Method used

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  • Composition for maintaining and/or improving memory/learning ability, and food, drug, and feed containing said composition
  • Composition for maintaining and/or improving memory/learning ability, and food, drug, and feed containing said composition
  • Composition for maintaining and/or improving memory/learning ability, and food, drug, and feed containing said composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0096] (Example 1) Production of an agent (granule) for maintaining and / or improving memory and learning ability

[0097] Lactobacillus henae SBT0316 strain was inoculated into edible synthetic medium (containing 0.5% yeast extract and 0.1% trypticase peptone) at 5% by weight, incubated at 38°C for 15 hours, and then passed Bacterial cells were collected by centrifugation. The recovered bacterial cells are freeze-dried to obtain a freeze-dried powder of bacterial cells. 1 gram of freeze-dried powder is mixed with 5 g of lactose, and the mixture is formed into granules to obtain the agent for maintaining and / or improving memory and learning ability of the present invention.

Embodiment 2

[0098] (Example 2) Production of an agent (powder) for maintaining and / or improving memory and learning ability

[0099] According to the provisions of the 13th revision of the Japanese Pharmacopoeia Guideline General Formulation (Japanese Pharmacopoeia Guideline General Formulation) "powder", 400 g of lactose (Japanese Pharmacopoeia) and 600 g of potato starch (Japanese Pharmacopoeia) were added to 10 g of Example 1 obtained. The freeze-dried powder of Lactobacillus henae SBT0316 strain is mixed uniformly to produce the memory and learning ability maintenance and / or improvement agent of the present invention.

Embodiment 3

[0100] (Example 3) Production of a nutritional composition for maintaining and / or improving memory and learning ability

[0101] The Lactobacillus henae SBT0316 strain was inoculated into an edible synthetic medium (containing 0.5% yeast extract and 0.1% tryptone peptone) at 5% by weight, and cultured at 38°C for 15 hours. The bacterial cells were then collected by centrifugation, and the collected bacterial cells were freeze-dried. To 40 g of vitamin C or 40 g of a mixture containing equal amounts of vitamin C and citric acid, 100 g of granulated sugar and 60 g of a mixture containing equal amounts of cornstarch and lactose, 40 g of this freeze-dried powder of freeze-dried powder was added and mixed. The mixture is packaged in a bag, thereby producing the nutritional composition for memory and learning ability maintenance and / or improvement of the present invention.

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Abstract

The purpose of the present invention is to provide a drug, a food, a drink, and a feed which are effective in preventing and / or improving a decrease in memory / learning ability due to aging. Provided is a novel microorganism having an effect of preventing and / or ameliorating a decrease in memory / learning ability due to aging. More specifically, the microorganism is characterized by belonging to the genus Lactobacillus, the genus Bifidobacterium, the genus Streptococcus, the genus Leuconostoc or the genus Pediococcus. The invention also relates to a method. The microorganism is characterized by belonging to any one of the following: Lactobacillus acidophilus, Lactobacillus gasseri, Lactobacillus henryi, Lactobacillus johnsonii, Lactobacillus delbrueckii subsp. Delbrueckii, Bifidobacterium catenaria, Bifidobacterium pseudolongum, Bifidobacterium bifidum, Bifidobacterium breve, Bifidobacterium longum, Streptococcus thermophilus, Leuconostoc mesenteroides subsp. Dextran, and Leuconostoc lactis. And pediococcus acidilactici and pediococcus pentosaceus.

Description

technical field [0001] The present invention relates to an agent for preventing or ameliorating the decline of memory and learning ability with aging (aging) and / or a food and drink having a preventive or ameliorating effect for the decline of memory and learning ability with aging (aging). Background technique [0002] In Japan, in 2010, the percentage of the elderly population over the age of 65 has exceeded 21% of the total population, and the country has entered a super-aging society. The percentage of older people is expected to continue to increase and is said to reach 40% by 2060. In this context, addressing the growing elderly population, such as health care and welfare issues, is a top priority. [0003] As the geriatric population increases, cognitive impairment such as decline in memory and learning ability and dementia among the middle-aged age groups has become a problem. It is generally believed that the microscopic structure of neurons in the brain changes w...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/135A23C9/123A23K10/18A23L2/52A61K35/747A61P25/28A61K35/745A61K35/744
CPCA23L33/135A23C9/1234A23K10/18A23L2/52A61K35/747A61K35/745A61K35/744A61P25/28A23V2002/00A23V2400/137A23V2400/151A23V2400/113A23V2400/321A23V2400/413A23V2400/427A23V2400/521A23V2400/517A23V2400/519A23V2400/249A23V2400/533A61K2300/00A23V2200/322A23K10/16A23L2/382C12N1/205C12R2001/01C12R2001/46C12R2001/225C12R2001/23A23V2400/145A23L2/38A23C9/12C12N1/20A23L33/40A23C9/123A61K9/0056A61K35/742A61K47/36A61K47/44A61K47/46A23V2400/11
Inventor 日暮聪志野间健太郎森郁惠中野俊诗塚田祐基
Owner SNOW BRAND MILK PROD CO LTD
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