The objective of this invention is to provide: aerobic-tolerant
Bifidobacterium spp. capable of being cultured under aerobic conditions, a method for culturing the same and a method for screening it, and a composition comprising aerobic-tolerant
Bifidobacterium spp. and a method for manufacturing the same. The present invention that solves this problem is a method for culturing
Bifidobacterium bacteria, comprising the step of culturing Bifidobacterium
bacteria having any one of the following (1) to (7) under aerobic conditions: (1) a
gene consisting of a
base sequence shown in sequence number 1 or 2; (2) a
gene having more than 90% identity with a
base sequence shown in sequence number 1 or 2; (3) a
gene consisting of a
base sequence in which 1 to several bases are missing, substituted, or added to a base sequence shown in sequence number 1 or 2; (4) a gene consisting of a base sequence of
DNA that can hybridize under strict conditions with
a DNA consisting of a complementary sequence of a base sequence shown in sequence number 1 or 2; (5) a gene consisting of a degenerate isomer of a base sequence shown in sequence number 1 or 2; (6) a gene encoding a
protein consisting of an
amino acid sequence shown in sequence number 3 or 4; (7) a gene encoding a
protein consisting of an
amino acid sequence in which 1 to several amino acids are missing, substituted, or added to an
amino acid sequence shown in sequence number 3 or 4.