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Cosmetic compsns. contg. vitamin B3

A technology of composition and vitamin, applied in the direction of cosmetics, cosmetics, cosmetic preparations, etc., can solve problems such as reducing efficacy

Inactive Publication Date: 2005-05-11
PROCTER & GAMBLE CO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, dissolution reduces vitamin B 3 Efficacy of similar compounds in contact with skin

Method used

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  • Cosmetic compsns. contg. vitamin B3
  • Cosmetic compsns. contg. vitamin B3
  • Cosmetic compsns. contg. vitamin B3

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0089] I. Preparation of Analytical Samples:

[0090] 1) Place the emollient in a pre-weighed bottle, followed by vitamin B 3 Saturated compounds;

[0091] 2) Shake the bottle and let stand in an external bath at 30°C for 1 hour. Stir the contents of the bottle with a small stir bar. If no precipitation occurs in the bottle, more niacinamide can be added later. Repeat the operation until precipitation occurs. Allow the sample to remain in the external bath for an additional 48 hours to ensure saturation;

[0092] 3) Draw the saturated emulsion into the syringe;

[0093] 4) Fit a 0.45 micron filter (Gelman Acrodisc) to the tip of the syringe and filter the emollient into additional pre-weighed assay vials;

[0094] 5) Utilize HPLC to analyze the emollient, and determine the content of nicotinamide therein.

[0095] II. Analysis:

[0096] Approximately 0.25 g of sample was weighed (sample weight) into a 15 mL plastic screw cap centrifuge tube. Samples were mixed with ap...

Embodiment

[0100] The cosmetic formulations described in Examples I-X illustrate specific embodiments of the cosmetic compositions of the present invention, but do not limit the invention. Other modifications can be made by those skilled in the art without departing from the spirit and scope of this invention. Embodiments of these exemplary cosmetic compositions of the invention provide enhanced vitamin B 3 Improves the skin penetration of the compound and improves the stability of the cosmetic composition.

[0101] All exemplified compositions may be prepared using conventional formulation and mixing techniques. The formulation and mixing techniques are described in detail in Harry's Cosmetology , pp.119-141 and 314-354 (J.B.Wilkinson and R.J.Moore 7thed 1982) and Cosmetics: Science and Technology , pp. 1-104 and 307-422 (M.S. Balsam and E. Sagarin 2nd ed 1972), both of which are hereby incorporated by reference in their entirety. Component amounts are given in weight percent and ex...

Embodiment I

[0102] Example 1 - Lipstick Composition

[0103] Component Content (weight percent)

[0104] Ozone wax 5.00

[0105] Candelilla Wax 3.00

[0106] Carnauba Wax 2.00

[0107] Cetyl Alcohol 2.00

[0108] Cetyl Lactate 2.00

[0109] Tocopheryl Palmitate 0.50

[0110] Propyl paraben 0.10

[0111] Vitamin E acetate 0.05

[0112] Isopropyl isostearate 13.97

[0113] Octyl Hydroxystearate 5.20

[0114] Paraffin 2.50

[0115] Niacin Tocopherol (23%) + Castor Oil (77%) 21.74

[0116] Dispersion (ball milling) 1

[0117] Acetyl lanolin 6.33

[0118] Mica SVA 10.00

[0119] Mica SVA 10.00

[0120] Pigment paste (30% pigment / 70% castor oil) 25.61

[0121] 1 Crystalline tocopheryl nicotinate was mixed with castor oil and ball milled to achieve an average crystal particle size of about 0.11 μm to about 200 μm.

[0122] The milled tocopheryl niacin / castor oil mixture is mixed with the remaining ingredients of the above formulation and added to a vessel fit...

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Abstract

Disclosed are cosmetic compositions including lipsticks, comprising from about 0.01% to about 50%, by weight, of a crystalline vitamin B3 compound having an average particle size of from about 0.01 mum to about 200 mum; from about 1% to about 90%, by weight, of an emollient component; and from about 1% to about 90%, by weight, of a solidifying agent. The compositions provide improved skin feel of crystalline vitamin B3 compounds when applied to skin.

Description

field of invention [0001] The present invention relates to compositions containing crystalline B vitamins dispersed in an emollient and oil phase 3 Cosmetic compositions for topical use. Background of the invention [0002] Niacin, also known as vitamin B 3 , is the common name for niacin. The physiologically active form of niacin is niacinamide, which is also a vitamin B 3 member of a family of compounds. Niacin and nicotinamide (niacinamide) function in the body as components of two enzymes: nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). Until recently, these B vitamins 3 The class of compounds is only used specifically for the treatment of niacin deficiency and pellagra. [0003] However, vitamin B 3 The class of compounds is suitable for use in the field of skin care actives. British Patent 1,370,236 describes skin lightening compositions containing 0.5% to 10% niacin. Similarly, US Patent 4,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K7/027A61K7/032A61K7/32A61K7/48A61K8/00A61K8/49A61K8/67A61Q1/00A61Q1/04A61Q1/06A61Q1/10A61Q15/00
CPCA61K8/675A61Q1/06A61Q1/10A61Q15/00A61K8/67A61Q1/04
Inventor D·W·沃尔林M·L·瓦特
Owner PROCTER & GAMBLE CO