Laser spectrum cancer diagnostic device with diode laser
A diode laser and diagnostic instrument technology, which is applied in the fields of radiological diagnostic instruments, diagnosis, and clinical application of radiological diagnostics, can solve the problems of slow diagnosis of malignant tumors, inconvenient to carry, and difficult to distinguish the degree of deterioration.
Inactive Publication Date: 2006-05-24
HARBIN INST OF TECH
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[0003] In order to solve the current problems of slow diagnosis of malignant tumors, difficulty in distinguishing the degree of deterioration, bulky instruments, and inconvenient carrying, the present invention proposes a diagnostic method that uses a diode laser as a light source and utilizes the fluorescence characteristics of the measured tissue to diagnose malignant tumors. instrument
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[0005] refer to figure 1 , it is made up of diode laser 4, lens 1, fiber coupling device 2, lens 3, optical filter 5, optical fiber 6, grating spectrometer 7, CCD detector 8 and microcomputer 9, and present embodiment utilizes a diode laser 4 as The excitation light source has an output power of 10-30 milliwatts and an output wavelength of 405 nanometers. The light output by the diode laser becomes parallel light through lens 1. Both lens 1 and lens 3 are convex lenses. The focal length of lens 1 is 3-5 mm. And coated with an anti-reflection coating with a wavelength of 405 nanometers, the parallel light passes through the optical filter 5, and the parallel light is then converged into the optical fiber 6 through the optical fiber coupling device 2. The material of the optical fiber 6 is quartz, and the diameter is 0.6 ~ 1mm. The optical fiber 6 irradiates the target tissue to induce the tissue and the photosensitizer to emit fluorescence. The fluorescent light returns through...
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The invention discloses a disease diagnosis instrument-a diode laser laser spectrum cancer diagnosis instrument. It consists of diode laser (4), lens (1), fiber coupling device (2), lens (3), optical filter (5), optical fiber (6), grating spectrometer (7), CCD detector (8) and Composed of a microcomputer (9), the diode laser (4) is used as the excitation light source; then it is collected into the optical fiber (6) through (2), and when the light is irradiated on the human tissue through the optical fiber (6), the emitted fluorescence is again Return along the original path through the optical fiber (6), when the fluorescence passes through (5), the fluorescence is refracted, and converges to (7) through the lens (3), and uses (8) to receive the fluorescence in the corresponding spectral range, and is combined with (8) ) is connected to a microcomputer (9) to display the fluorescence spectrum of the desired band. The advantages of this instrument are low cost, miniaturized equipment, accurate and fast diagnosis. Due to the small size of the diode laser, most of the products developed with it can be made portable, which provides convenience and possibility for door-to-door service and the use of the same set of equipment by multiple departments. .
Description
technical field [0001] The invention relates to a disease diagnosis instrument, which uses laser-induced fluorescence technology and spectral analysis technology, and uses a diode laser and a photosensitizer to judge whether the tissue is cancerous and the degree of tumor malignancy. Background technique [0002] Malignant tumors are diseases that seriously threaten human life. Therefore, exploring methods and techniques for early diagnosis and effective treatment has always been one of the most urgent research topics in medicine. Most of the doctors' diagnosis of cancer still relies on the doctor's experience and biopsy examination, with a certain degree of blindness, and early lesions are easily missed and misdiagnosed. Laser medicine is an emerging discipline of modern medicine. It integrates high and new technologies in the fields of laser, spectroscopy, fiber optics, optical information processing, and photodynamics, and applies them to the diagnosis and treatment of d...
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Inventor 张治国赵广播刘佳雯杨玉强朱瑞滨刘玉强
Owner HARBIN INST OF TECH