Anti EB virus resulted tumour polypeptide, and its use and preparing method

An Epstein-Barr virus and tumor technology, applied in the field of anti-Epstein-Barr virus-induced tumor polypeptide and its application and preparation, can solve the problem that the specific markers on the cell surface are rarely found, and achieve the effect of specific targeting
CN1274829CActive Publication Date: 2006-09-13畿晋庆堂国际生物技术有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
畿晋庆堂国际生物技术有限公司
Publication Date
2006-09-13

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Abstract

The present invention relates to molecules that are capable of killing cells. The molecules comprise a targeting agent and a channel-forming moiety. The molecules may be polypeptides. The present invention also relates to polynucleotide sequences encoding the polypeptides of the invention. In a preferred embodiment, the channel-forming moiety comprises a colicin and the targeting agent is an antibody. Methods of treatment by administering the molecules of the present invention are also provided.
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Description

technical field

[0001] The invention relates to a gene, recombinant plasmid, polypeptide and application and preparation method of anti-Epstein-Barr virus-induced tumor polypeptide. Background technique

[0002] Malignant tumors are a huge threat to human health. There are about 7 million patients who die from malignant tumors every year in the world, among which China accounts for one-sixth. Malignant tumors are the second cause of death in my country. Because its etiology, pathogenesis, and clinical manifestations have not yet been clarified, so the control effect is not ideal. Existing anti-tumor drugs play an important role in the treatment of tumors. Although they have achieved certain curative effects on some tumors, they still have defects such as poor selectivity for tumor cells, many and serious immunosuppression and adverse reactions, and drug resistance.

[0003] In recent years, great progress has been made in the basic and clinical r...

Claims

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