Spleen invigorating appetizing effervescence tablet for children and preparation method thereof
A technology for invigorating spleen appetizers and effervescent tablets, which can be applied to pharmaceutical formulas, medical preparations containing active ingredients, drug delivery, etc., and can solve problems such as slow effect and long disintegration time
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Examples
Embodiment 1
[0063] Effects on Diarrhea in Mice with Spleen Deficiency
[0064] Experimental animals: mice, weighing 20-22g, both male and female.
[0065] Experimental drug: normal saline (provided by the research laboratory of Guangdong Tianzhijiao Drug Development Co., Ltd.)
[0066] Erkangning Effervescent Tablets (provided by the research laboratory of Guangdong Tianzhijiao Drug Development Co., Ltd.)
[0067] Erkangning Syrup (Fuling Pharmaceutical Factory of Taiji Group)
[0068] Experimental method: Take mice, use laxatives to induce spleen-deficiency diarrhea model, divide them into normal saline group, Erkangning syrup group, and Erkangning effervescent tablet group, and administer them by intragastric administration. , normal saline group isovolumic and unequal, administered 3 times a day, continuously administered for 7 days, observing the number of defecation of mice on the 8th day, weighing the mice, the results are shown in Table 9:
[0069]
[0070] Compared wi...
Embodiment 2
[0072] Effect on gastric residual rate in mice
[0073] Experimental animals: mice, weighing 20-22g, both male and female.
[0074] Experimental drug: normal saline (provided by the research laboratory of Guangdong Tianzhijiao Drug Development Co., Ltd.)
[0075] Erkangning Effervescent Tablets (provided by the research laboratory of Guangdong Tianzhijiao Drug Development Co., Ltd.)
[0076] Erkangning Syrup (Fuling Pharmaceutical Factory of Taiji Group)
[0077] Experimental method: Take mice, fast for 12 hours, and divide them into 3 groups at random, divided into normal saline group, Erkangning syrup group, and Erkangning effervescent tablet group, and administer them by intragastric administration. / Each time, the normal saline group was equal to different volumes. One hour after the administration, each mouse was fed with 0.2ml of methyl orange solution. After 20 minutes, the stomach tip was taken, gastric lavage was performed with distilled water, and the supernatant ...
Embodiment 3
[0099] (1) bulk drug of the present invention is:
[0100] Codonopsis 300g, Astragalus 100g, Atractylodes macrocephala 300g, Poria cocos 200g, yam 300g, Coix seed 300g, Radix radix 300g, Polygonum multiflorum 300g, Jujube 100g, Hawthorn 100g, Fried malt 100g, 200 grams of mulberry branches, 0.6ml of tangerine peel oil.
[0101] (2) Take the above-mentioned twelve Chinese herbal medicines, add 10 times of water, decoct twice for 3 hours each time, filter, combine the extracts, concentrate to 50°C when the relative density is 1.15, add ethanol to make the alcohol content 65%, stand still for 30 hours, take the supernatant, recover ethanol to the utmost, concentrate, dry, pulverize to obtain the extract;
[0102] (3) Get tangerine peel oil, according to the ratio of volatile oil: hydroxypropyl-β-cyclodextrin=1: 25, high-speed stirring for 5 hours (rotating speed is 6000 rpm), cooled to room temperature, refrigerated for 36 hours, suction filtered, The clathrate was washed twice...
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More