Mycobacterium Smegmatis preparation and use thereof

Abstract

The invention provides a mycobacterium Smegmatis preparation, which is prepared from Mycobacterium Smegmatis through fragmenting decomposition, such as heavy pressure fragmenting method or ultrasonication method. The Mycobacterium Smegmatis is a safe and effective immuno-modulatory agent for enhancing normal body immune function, accelerating the restoration of the low body immune functions and inhibiting over-strong immune response of the immune sthenic body, i.e. bidirectional immunological control response.

Description

technical field

[0001] This application relates to the field of biotechnology, immunology and the field of pharmaceutical use of microbial products, and specifically relates to the verification of immune regulation function of Mycobacterium smegmatis preparations and its use in the prevention and treatment of tuberculosis, asthma, hepatitis B and other diseases. Background technique

[0002] Tuberculosis is one of the top ten diseases that endanger human health announced by the World Health Organization (WHO). According to WHO estimates, nearly 1 / 3 of the world's people have been infected with Mycobacterium tuberculosis, and there are 20 million active tuberculosis patients, an increase of 800 every year. 10,000 to 10 million patients and 3 million deaths from TB; if control strategies are not further improved, it is estimated that between 2000 and 2020, 1 billion people will be infected with TB, 200 million people will suffer from TB disease, and 35 million people will die ...

Images