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Medicinal composition with synergetic function

A composition and drug technology, applied in the field of medicinal compositions containing natural plant extracts or monomers, can solve problems such as no suggestion or attempt, no scientific basis provided, etc.

Active Publication Date: 2007-06-06
YUNNAN BIOVALLEY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] What is even more unfavorable is that so far, the existing technology has not provided scientific basis for the basic issues such as whether ginkgo can be used in combination with peony and whether the mechanism of action of the two is additive, synergistic or antagonistic.
As for whether the two can be used in combination for other diseases (such as diabetes, Alzheimer's disease), there is no similar suggestion or attempt in the prior art

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0179] Example 1 Capsules

[0180] Take 5g of Ginkgo biloba extract (purity 97%, of which flavonoids are 24%, lactones are 6%), take 5g of red peony extract (containing 20% ​​paeoniflorin), add starch, mix well, granulate, crush and sieve , The granules are dried and then filled into 20 hard capsules. After testing, each capsule contains 15mg of ginkgolides and 50mg of paeoniflorin.

Embodiment 2

[0181] Example 2 Tablets

[0182] Take 8g of ginkgolide and 60g of paeoniflorin, grind the powder through a 80-mesh sieve, add an appropriate amount of dextrin, mix well, first wet it with 40-60% ethanol, then granulate with starch slurry, sieving and drying at 80°C. The whole powder (passed through a 14-mesh sieve) is evenly mixed with 100-mesh magnesium stearate into the granules to make 1000 tablets, which are then coated. After testing, each tablet contains 8 mg of ginkgolide and 60 mg of paeoniflorin.

Embodiment 3

[0183] Example 3 Soft capsules

[0184] Take 40 g of ginkgo flavonoids and 20 g of paeoniflorin, add them to vegetable oil and mix well, use gelatin as the shell material, and compress them into 1000 soft capsules. After testing, each capsule contains 40mg of ginkgo flavonoids and 20mg of paeoniflorin.

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PUM

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Abstract

The present invention relates to a kind of medicine composition, and its preparation process and application. The said medicine composition contains mainly bilobalide and paeoniflorin. The medicine composition of the present invention may be used in treating and preventing diabetes, senile dementia and cardiac and cerebral vascular diseases and in preventing recurrence of cardiac and cerebral vascular diseases.

Description

Technical field [0001] The present invention relates to a pharmaceutical composition, specifically, a pharmaceutical composition containing natural plant extracts or monomers for the treatment and / or prevention of cardiovascular and cerebrovascular diseases, diabetes, and Alzheimer's disease, and for preventing Recurrence of cardiovascular and cerebrovascular diseases. Background technique [0002] With the rapid development of modern science, people pay more and more attention to "natural" medicines. In recent years, the pharmaceutical industry has done a lot of work in the research of medicinal plants for the prevention and treatment of cardiovascular and cerebrovascular diseases, diabetes and other diseases, and strengthened the analysis and research of biologically active substances in order to further clarify their efficacy. However, the results achieved are limited. This is mainly due to the complicated pathogenesis of cardiovascular and cerebrovascular diseases, diabetes a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7048A61K36/71A61K36/16A61P3/10A61P25/28A61P9/00
Inventor 林艳和潘锡平林谷风
Owner YUNNAN BIOVALLEY PHARMA CO LTD
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