Electrochemical biosensor test strip, fabrication method thereof and electrochemical biosensor

A biosensor and electrochemical technology, applied in the field of electrochemical biosensors, can solve the problems of easy disengagement, low detection efficiency, and difficult fixation of reagents

Inactive Publication Date: 2002-05-15
ALL MEDICUS CO LTD
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  • Summary
  • Abstract
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  • Claims
  • Application Information

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Problems solved by technology

[0009] However, the existing commercially available electrochemical biosensor test strips, including the biosensor test strip described in the above-mentioned patent, have the following serious problems: because the electrodes are all fabricated on the plane of the substrate , and the reagents including enzymes are immobilized on the electrode, and during the immobilization process, the reagents in

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  • Electrochemical biosensor test strip, fabrication method thereof and electrochemical biosensor
  • Electrochemical biosensor test strip, fabrication method thereof and electrochemical biosensor
  • Electrochemical biosensor test strip, fabrication method thereof and electrochemical biosensor

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Embodiment Construction

[0026] Preferred embodiments of the present invention may be best understood with reference to the accompanying drawings. In the drawings, the same reference numerals denote the same and corresponding parts, respectively. The preferred embodiments are for illustrative purposes only and are not intended to limit the invention.

[0027] 2 is a perspective view schematically showing the structure of a test strip of an electrochemical biosensor according to the present invention. As can be seen from the figure, the test strip of the electrochemical biosensor of the present invention comprises an insulating substrate 41 or 42 on which a press working or vacuum molding method ( Figure 2A ). Imprint or by etching ( Figure 2B ) to form grooves 45 or 46. The electrode 44 is mounted on the insulating substrate 41 or 42 . The grooves 45 or 46, whether stamped or etched, function to ensure that the corresponding reagent (not shown) is immobilized thereon.

[0028]In this structure...

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Abstract

Electrochemical biosensor test strip, fabrication method thereof and electrochemical biosensor are disclosed. The electrochemical biosensor test strip is fabricated by cutting a groove in a first insulation base in the breadth direction, forming two electrodes parallel to length direction on the first insulation base by sputtering using shadow mask, fixing a reaction material comprising an enzyme which reacts an analyte and generates current corresponding to the concentration of analyte across the two electrodes on the groove of the insulation base, and affixing a cover to the first insulation base. The groove of the first insulation base and the cover make a capillary at the position where the reaction material is fixed. The fabrication method can lower the cost for fabricating the test strip by forming thin electrodes.

Description

technical field [0001] The present invention relates to a test strip for an electrochemical biosensor for quantitative analysis of an analyte of interest, a method of manufacture thereof, and an electrochemical biosensor using the test strip. Background technique [0002] In the medical field, electrochemical biosensors are widely used to analyze biological substances including blood. Among such biosensors, electrochemical biosensors utilizing enzymes are the most predominant biosensors in hospital or clinic laboratories because of their ease of use and high measurement sensitivity, which allows for rapid acquisition of test results. For electrochemical biosensors, an electrode method has recently been widely adopted. For example, in electrode systems fabricated by screen printing, analytes of interest can be quantitatively measured by immobilizing reagents including enzymes on the electrodes, adding a sample, and then applying a voltage across the elec...

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Application Information

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IPC IPC(8): G01N33/483A61B5/145A61B5/1468A61B5/1486G01N1/28G01N27/30G01N27/327G01N33/487G01N33/543
CPCG01N33/5438G01N27/3272G01N27/3271G01N27/327
Inventor 柳畯午李进雨
Owner ALL MEDICUS CO LTD
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