62results about How to "Accurate quantitative determination" patented technology

The invention provides a method for detecting the content of impurity elements in electrolyte of a vanadium cell. The method comprises the following steps: measuring primary sample solution of electrolyte of the vanadium cell as per the proportional relation of dilution by 5 to 10 times, placing the primary sample solution in a measuring flask, adding water for dilution to fix volume, adding standard solution of elements to be detected with different volumes in prepared matrix matching base solution formed by vanadium ion, hydrogen ion and sulfate ion, finally preparing standard solution of elements to be detected with different concentration gradients, drawing a standard curve of standard solution of elements to be detected, inspecting linearly dependent coefficients, determining the primary sample solution, which is prepared through dilution, of electrolyte of the vanadium cell, , multiplying a detection result by the dilution ratio to obtain the content of impurity elements in electrolyte of the vanadium cell. The method has good precision and reproducibility of preparation of sample solution and instrument measurement.

Electrochemical biosensor test strip, fabrication method thereof and electrochemical biosensor are disclosed. The electrochemical biosensor test strip is fabricated by cutting a groove in a first insulation base in the breadth direction, forming two electrodes parallel to length direction on the first insulation base by sputtering using shadow mask, fixing a reaction material comprising an enzyme which reacts an analyte and generates current corresponding to the concentration of analyte across the two electrodes on the groove of the insulation base, and affixing a cover to the first insulation base. The groove of the first insulation base and the cover make a capillary at the position where the reaction material is fixed. The fabrication method can lower the cost for fabricating the test strip by forming thin electrodes.

There is provided a fluorescent X-ray analysis apparatus in which a detection lower limit is improved, and it is possible to quantify a trace aimed element having been contained not only in a sample whose main component is a heavy element but also in a sample whose main component is a light element. The fluorescent X-ray analysis apparatus possesses a sample base supporting the sample, an X-ray source irradiating a primary X-ray with a predetermined irradiation position being made a center, and a detector disposed toward the irradiation position and detecting a fluorescent X-ray generated from the sample. The sample base has a detachable sample holding tool fixing the sample while being approached to the X-ray source and the detector, and a measurement is possible by selectively disposing the sample in any one of a 1st inspection position in which an irradiated face is coincided with the irradiation position, or a 2nd inspection position in which the sample is fixed to the sample holding tool, an irradiated face is approached to the X-ray source, and an inspected face is approached to the detector.

The invention discloses a quality control method for edaravone and an edaravone-containing preparation. In the method, an impurity, namely, 2,2',4,4'-tetrahydrophthalic anhydride-5,5'-dimethyl-2,2'-diphenyl-[4,4'-di-3H-parazole]-3,3'-dione in the edaravone and an edaravone preparation is determined quantitatively by photoelectric technology. By the technical scheme of the invention, the qualities of the edaravone and an edaravone-containing medicament preparation can be evaluated and controlled more reliably and accurately.

The invention belongs to the field of pharmaceutical analytical chemistry, and particularly relates to two methods for analyzing and measuring potential genotoxic impurities in pantoprazole sodium anda synthetic starting material 5-difluoromethoxy-2-mercapto-1H-benzimidazole thereof. According to the method, octadecylsilane chemically bonded silica is used as a stationary phase, and a mass spectrometry detector is used for analysis and determination; the mobile phase is an aqueous solution containing acetonitrile, methanol and organic ammonium salt; the structural types of the potential genotoxic impurities comprise halogenated methylpyridine compounds, azaaryl N-oxides, N-acylated aminobenzene compounds, aromatic amines compounds and nitrobenzene compounds. According to the method, the effective separation of potential genotoxic impurities in pantoprazole sodium and synthesis starting raw materials of pantoprazole sodium can be realized, the genotoxic impurities can be accurately andquantitatively determined; the method is high in sensitivity and specificity; the experimental operation is simple, convenient and rapid, and the method has important significance for quality controland medication safety of pantoprazole sodium.

The invention provides an analysis system and an analysis method of two-dimensional energy associated laser induced breakdown spectroscopy. The analysis system comprises a laser, a spectrograph, a delay generator, an optical fiber, a sample and a computer, wherein the laser is used for periodically transmitting pulse laser to strike the sample; the delay generator is respectively connected with the laser and the spectrograph and used for triggering a spectrograph acquisition signal according to a preset delay time; the spectrograph is respectively connected with the optical fiber and the computer and used for acquiring a plasma optical signal transmitted by the sample by virtue of the optical fiber. According to the analysis system and the analysis method of the two-dimensional energy associated laser induced breakdown spectroscopy, the conventional laser induced breakdown spectroscopy is carried out on a laser energy scale, so that the spectral signature can be clearly analyzed, and the detection capability and the repeatability of the conventional laser induced breakdown spectroscopy method can be improved.

A positive-pressure automatic spume proportionality mixer systems includes pressure water pipeline, spume pipeline and mixer pipeline. There are at least spume tank, spume purification apparatus, ram-type pump, spume application valve ball and back valve setup at the spume pipeline with spume tank at the beginning, the out spout pipeline of back valve joins with pressure water pipeline to mixer pipeline. A flow rate sensor is set at the aforementioned mixer pipeline and connects to control module with wires, the control module connects with parameter input and display module and machine controller connecting with electric motor drive ram-type pump. The system can implement whole automatic control spume mixing proportion with simple operation, accurate adjustment, stabilizing and reliable operation activity.

The invention relates to a content determination method for scutellarin and scutellarein in sculellaria barbata medicinal material and formula granule of sculellaria barbata medicinal material. The content determination method is characterized in that common isocratic elution is adopted, acetonitrile-methyl alcohol-0.1 percent phosphoric acid of which the volume ratio is 12.5:(15 to 16.2):(71.3 to 72.5) is taken as a mobile phase, and the contents of the scutellarin and the scutellarein in the sculellaria barbata medicinal material and the formula granule of the sculellaria barbata medicinal material are simultaneously determined at a wavelength of 340+/-2nm. The method is simple, convenient, fast, and easy to popularize and master; the separations of wave crests on three different chromatographic columns are good. Compared with a method of recording under a sculellaria barbata medicinal material item of the first part of the pharmacopeia, the prominent improvement is that a sample treatment process is simplified, the time and cost are saved, the determination is advanced from single component determination of the scutellarin to the simultaneous determination of the two components, the quality controllability is improved, and the defects that impurity peaks exist and the content results are inaccurate are overcome.

A container and method for taking out contained product. The container comprises a container body, a pressure transfer channel, a control valve, a liquid taking channel and an outflow channel, the control valve contains a moving part. The moving part is at different positions along with variation of pressure applied to a variable pressure part, and connection and disconnection of the channels which between the pressure transfer channel and the outflow channel and between the liquid taking channel and the pressure transfer channel are determined by three positions of the moving part. The container can quantitatively take out contained product, is simple in structure and avoid the product to be oxidized or polluted.

The invention relates to the field of textile testing and discloses a method for tracing silk production places on the basis of a stable isotope technique. The stable isotope technique is adopted for tracing the silk production places by testing isotopic values of hydrogen, oxygen, carbon and nitrogen and strontium in mulberry leaves, mulberry twigs, silkworm cocoons and soil and isotopic values of hydrogen and oxygen in water samples, results are finally subjected to clustering analysis, and the silk production places are traced. Transfer and transformation of metabolites can be accurately and quantitatively determined by the aid of the stable isotope technique, and the silk production places can be scientifically and stably traced.

The invention relates to a fingerprint resistant film, in particular to a method for detecting the weight of the fingerprint resistant film. The method for detecting the weight of the fingerprint resistant film of a fingerprint-resistant electro-galvanized sheet comprises the following steps of: preparing dezincing solution and zinc standard solution; sampling; sample processing; detecting the total weight of a galvanized coating; detecting galvanized amount; and working out the weight of the fingerprint resistant film. By the method, the weight of the fingerprint resistant film can be directly, correctly and quickly detected, and the detection is not influenced by the change of fingerprint resistant raw material components and a production process.

The invention discloses a detection method of xylooligosaccharide. According to the method, a high-performance liquid chromatograph and an evaporative light scattering detector are used for performing qualitative and quantitative detection on small polymers, with different degrees of polymerization, in the xylooligosaccharide. The method is very high in detection sensitivity and can quantitatively detect the small polymer components in the xylooligosaccharide accurately; the separating effect is good; and the detecting repeatability is good.

The present invention provides genetic marker, method and reagent kit for detecting ox originated/sheep originated components in feed. Specifically, the present invention provides the D-loop doze nucleotide sequence of the ox originated/sheep originated components in feed and the primer and probe designed based on the sequence. The method may be used in convenient, fast and accurate qualitative and quantitative detection of ox originated/sheep originated components in feed.

The invention discloses pazufloxacin mesilate and a quality control method of an injection preparation. According to the method, high performance liquid chromatography is employed for performing quantitative determination on pazufloxacin mesilate and an impurity pazufloxacin mesilate dextroisomer in the preparation. The technical scheme provided by the invention is capable of relatively reliably and relatively accurately evaluating and controlling the quality of pazufloxacin mesilate and the injection preparation.

The embodiment of the invention provides a method and device for determining the porosity of cracks. The method comprises the following steps: acquiring an outcrop sample and a rock core sample in a target region; carrying out three-dimensional laser scanning on the outcrop sample, and establishing a reservoir geologic model of the target region; determining extension lengths of the cracks according to the reservoir geologic model of the target region; determining the opening, filling coefficients and penetration coefficients of the cracks according to the rock core sample; and determining the porosity of the cracks in the target region according to the extension lengths, opening, filling coefficients and penetration coefficients of the cracks. According to the scheme, the reservoir geologic model is established by virtue of the outcrop sample with a relatively good representation effect and is used for quantitatively determining the cracks; by combining with rock core data, the porosity of the cracks is accurately determined, so that the technical problems that the precision of the determined porosity of the cracks is low, and the accuracy is relatively poor in existing methods are solved, and the porosity of the cracks is rapidly, accurately and quantitatively determined.

The invention discloses a method for determining the minimal residual lesion level based on multiple amplification sequencing. Comprising the following steps: S1, sample treatment, S2, primer pool manufacturing, S3, single-ended amplification, S4, quality control, S5, purification, S6, mixed sequencing, S7, sequencing data analysis, and S8, minimal residual lesion level calculation. According to the determination method, simple and convenient single-ended amplification is used, the minimal residual lesion level can be accurately and quantitatively detected, an external reference is not needed, meanwhile, primer dimers can be prevented from being generated, the proportion of effective data is increased, and then the accuracy of determining the MRD level is improved.

The invention provides a method for detecting genetic toxic impurities of SM3 (4-amino-1-methyl-3-n-propylpyrazole-5-formamide) in a class 1 new drug aldenafil citrate bulk drug. A sample to be detected is detected by using a high performance liquid chromatography-mass spectrometry tandem method. According to the method provided by the invention, the genotoxic impurity 4-amino-1-methyl-3-n-propylpyrazole-5-formamide in the Adenafil can be effectively determined with ultrahigh sensitivity, so that strict quality control is implemented.

The invention belongs to the technical field of detection, and particularly relates to a detection method for simultaneously determining the content of eight compounds in glipizide drugs. The determination method is a reversed-phase high performance liquid chromatography method. The method can be used for simultaneously determining eight compounds in glipizide synthetic intermediates, glipizide bulk drugs and glipizide-containing drugs.

Methods for quantitatively determining a binding kinetic parameter of a molecular binding interaction, for example wherein the determination involves a complex sample, are provided. Aspects of embodiments of the methods include: producing a magnetic sensor device including a complex sample including a magnetic sensor in contact with an assay mixture including a magnetically labeled molecule to produce a detectable molecular binding interaction; obtaining a real-time signal from the magnetic sensor; and quantitatively determining a binding kinetics parameter of the molecular binding interaction from the real-time signal. Also provided are systems and kits configured for use in the methods.