Compound phytosterol with serum cholesterol-reducing action and preparing process thereof

A technology of phytosterols and cholesterol, which is applied in a drug field in the medical field, can solve problems such as toxic and side effects, and lower serum cholesterol, and achieve the effects of non-toxic and side effects, scientific product formula, and convenient carrying and taking

Inactive Publication Date: 2003-11-12
长沙市思胆诺生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The technical problem to be solved by the present invention is to solve the problem that common lipid-lowering drugs statins in the market have toxic and side effects, but phytosterols and phytostanox in crystal state cannot exert their effect of lowering serum cholesterol; the present invention provides a Compound phytosterol or compound phytostanol with scientific formula, easy to carry, no peculiar smell, non-toxic side effects, good lipid-lowering effect, can be taken alone or combined with other lipid-lowering drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0019] 1. Phytosterol or phytostanol / evening primrose oil or red pine seed oil, linseed oil, borage seed oil, deep-sea fish oil and other nutritional oil formulas

[0020] Put phytosterols (or phytostanol) and evening primrose oil (or Korean pine seed oil, linseed oil, borage seed oil, deep-sea fish oil, cod liver oil, vitamin E and other nutritional oils) in a heat-resistant container Mix well. The weight ratio is from 20:1 to 1:20. Heat to about 140 degrees Celsius. At this point the phytosterols are in a liquid state. Mix it with evening primrose oil, and cool to room temperature while stirring to form a solid or paste. Use a pulverizer to crush the solid mixture into powder, and the powder or paste mixture can be made into tablets, capsules, oral fast-moving agents, chewing agents, etc. with excipients and flavoring agents.

[0021] Formulation example 1 (tablet):

[0022] Phytosterol and evening primrose oil heated powder mixture, weight ratio 5:1 1 kg

[0023] Exci...

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PUM

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Abstract

The invention is a kind of compound plant ethanol which can decrease serum cholesterin and the manufacturing technique, the plant ethanol or plant sterol are heated and dispersed into other medium, there medium can be ovenproof edible emulsifier such as lactic acid stearate, sucrose fatty acid ester, they also can be nutrient oil such as evening primrose oil. Korean pine seed oil, flex seed oil, colored glaze lettuce seed oil, deepwater fish oil, bark soil, vitamin E, they may be the compound of the emulsifier and nutrient oil. The invention is scientific, convenient, no peculiar smell and no toxic side effect.

Description

Technical field: [0001] The invention relates to a medicine in the medical field, in particular to a medicine with the effect of lowering serum cholesterol. Background technique: [0002] Cardiovascular and cerebrovascular diseases, including coronary heart disease, myocardial infarction, cerebral haemorrhage, hypertension, etc., are common diseases among people in our country and many other countries, and are the number one cause of death of the urban population in our country. A large number of long-term clinical and laboratory studies have proved that high serum cholesterol, especially high levels of low-density lipoprotein (LDL) cholesterol is an independent risk factor for the development of coronary heart disease, myocardial infarction, and cerebral haemorrhage. Lowering serum cholesterol levels is recognized as an important measure to reduce and delay the occurrence and development of cardiovascular and cerebrovascular diseases. [0003] Human cholesterol comes from ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/575A61P3/06C07J9/00
Inventor 李安国
Owner 长沙市思胆诺生物技术有限公司
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