Neohouttuynin sodium freeze-dried powder-injection, and its prepn. method

A new technology of houttuynia sodium and freeze-dried powder injection can be applied in the field of medicine, which can solve the problems of inconvenience, easy precipitation, unstable storage period and the like, and achieve the effects of reducing irritation, prolonging storage period and improving bioavailability.
CN1459284AInactive Publication Date: 2003-12-03肖广常 +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
肖广常
Publication Date
2003-12-03
Estimated Expiration
Not applicable · inactive patent
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Abstract

A freeze-dried powder injection of neohouttuynine sodium for treating pelvic inflammation, annexitis and chronic cervicitis contains neohouttuynine sodium, one or more of cyclodextrin and its derivatives and excipient in a certain proportion. It is prepared through dissolving neohouttuynine sodium and cyclodextrin or its derivative in the water for injection, adding excipient, regulating the pH value, filtering, freezing, and sublimation drying.
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Description

(1) Technical field

[0001] The invention relates to a freeze-dried powder injection of neohouttuyfonate sodium for injection and a preparation method thereof, belonging to the technical field of medicine. (2) Background technology

[0002] Neohouttuydin Sodium is a synthetic product with the chemical name sodium laurylacetaldehyde bisulfite. This product is easily soluble in hot water, slightly soluble in water and ethanol, almost insoluble in chloroform and benzene, and almost insoluble in hydrogen Sodium oxide is easily soluble in the test solution, but it decomposes at the same time (National Drug Standard Chemical Drug Local Standard Rising National Standard Volume 5 P273). Moreover, the new houttuyfonate sodium has a fishy smell and a slight odor. The above-mentioned characteristics make its preparation and application subject to certain restrictions.

[0003] The usage and dosage of the instructions of the new houttuybein sodium injection in the national drug standard...

Claims

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