Antifungal compound of substitution benzyl triazole alcohols

A kind of technology of benzylamine triazole alcohol and compound, applied in the field of medicine
CN1539830AInactive Publication Date: 2004-10-27SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
Publication Date
2004-10-27
Estimated Expiration
Not applicable · inactive patent

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Abstract

An antifungus compound 1-(1H-1,2,4-triazole-1-yl)-2-(2,4- difluorophenyl)-3-[N-methyl-N-(4-substituted amino) benzylamino]-2-propanol and its salts, and its preparing process are disclosed. Its advantages are high curative effect, low poison and broad spectrum.
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Description

technical field

[0001] The present invention relates to the technical field of medicine, and is a new imazodiazole antifungal compound—a substituted benzylamine triazole alcohol compound, that is, 1-(1H-1,2,4-triazol-1-yl )-2-(2,4-difluorophenyl)-3-[N-methyl-N-(4-substituted amido)benzylamino]-2-propanol compounds and their salts and preparation methods . Background technique

[0002] In recent years, with the extensive application of broad-spectrum antibiotics, antineoplastic drugs, and immunosuppressants, the widespread implementation of radiotherapy and organ transplantation, the widespread development of catheters and intubations, and the rapid increase in immunocompromised patients, especially AIDS patients, have resulted in Fungal infections, especially deep fungal infections, have risen sharply, and deep fungal infections have become the main cause of death from major diseases such as AIDS and tumors. However, as far as the antifungal drug...

Claims

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