Carbazochrome Sodium Sulfonate infusion and its preparation method

Abstract

The present invention belongs to the field of medicine technology. The Carbazochrome liquid contains Carbazochrome 0.002-0.5 wt%, antioxidant 0-10 wt%, osmotic pressure regulator 0.8-75 wt%, and injection water 20-99.1 wt%. The preparation process of the Carbazochrome liquid includes dissolving osmotic pressure regulator with partial injection water in a compounding tank; adding injection level active carbon through heating and stirring for adsorption for 30 min; filtering and decarbonizing with titanium rod and adding rest injection water to obtain the solution I; dissolving Carbazochrome and antioxidant in solution I, adding injection level active carbon for adsorption for 30 min, filtering and decarbonizing with titanium rod, regulating pH value, fine filtering, detecting, packing in bottle, disinfecting and other steps. The medicine is used in intravenous transfusion for treating various hemorrhage diseases.

Description

(1) Technical field

[0001] The invention relates to a sodium carboxysulfonate infusion solution and a preparation method thereof, belonging to the technical field of medicine. (2) Background technology

[0002] Sodium carboxylate is a new generation of vascular enhancer and a vascular hemostatic drug with excellent curative effect. It was firstly developed by Jiangsu Wuzhong Industrial Co., Ltd. Suzhou No. 6 Pharmaceutical Factory and experts from China Medical University. And it has a wide range of applications and is widely used in clinical practice. Its domestically marketed dosage forms are sodium carboxylate sulfonate tablets and sodium carboxylate sulfonate for injection. Sodium carboxylate sulfonate for injection often needs to be compatible with normal saline or glucose solution in clinical applications. Intravenous drip (Li Lianhua et al. Observation on the efficacy of sodium carboxylate sulfonate. Zhonghua Clinical Medicine, 2002, Vol. 3, No. 24, P39), which brough...