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Ginseng-gaboderma lucidum tranquilizing dripping pill and its preparing method

A technology of Shenzhi Anshen and dripping pills, which is applied in the field of oral preparations of pharmaceutical compositions, can solve the problems of unfavorable overall health level, low dissolution rate, inconvenient taking or carrying, etc., and achieves benefits for labor protection, accelerated dissolution and absorption, The effect of improving bioavailability

Inactive Publication Date: 2005-10-19
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
However, syrup oral preparations also have disadvantages such as low drug content, difficulty in taking and measuring accurately, inconvenient taking or carrying, etc.
[0007] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0030] Now with several groups of specific examples, the preparation method of the Shenzhi Anshen dripping pills of the present invention will be further described.

[0031] Group 1: Tests with a single matrix

[0032] 1. Raw materials: Yunzhi polysaccharide, ginseng stem and leaf saponins

[0033] 2. Substrate: polyethylene glycol (1000、2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. One or a mixture of two or more pharmaceutical carriers;

[0034] 3. Proportion: in g or kg, by weight

[0035] Yunzhi polysaccharide: ginseng stem and leaf saponin = 12.5:1

[0036] (Yunzhi polysaccharide + ginseng stem and leaf saponin): matrix = 1:1~1:9;

[0037] 4. Prepare according to the process given in [Preparation Method] 4-7, and you can get different specifications of Shenzhi Anshen Dropping Pills.

[0038] [test results]

[00...

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PUM

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Abstract

The present invention relates to one medicine composition for treating deficiency of vital energy yin, insomnia and dreaminess, palpitation and hard breath, valetudinarianism, etc. and the medicine composition is prepared into rally taken preparation, especially tranquilizing dripping pill, with Coriolus Versicolor polysaccharide and ginseng stem and leaf saponin as active medicine components. The present invention has high bioavailability, fast medicine release, fast acting, high medicine component content and other advantages.

Description

technical field [0001] The present invention relates to a kind of medicinal composition which has the effects of nourishing qi and nourishing yin, calming the nerves and improving intelligence, and is used for the treatment of diseases such as deficiency of qi and yin, insomnia and dreaminess, palpitation, shortness of breath, protracted illness and infirmity. Saponin is an oral preparation of a pharmaceutical composition prepared from active pharmaceutical ingredients. Background technique [0002] According to the preparation method given in the national drug standard WS-10656 (ZD-0656)-2002, Shenzhi Anshen Oral Liquid, which is prepared according to the preparation method given in WS-10656 (ZD-0656)-2002, is a kind of medicine that has the functions of nourishing qi and nourishing yin, calming the nerves and improving intelligence, and is used for deficiency of qi and yin. Syrup-based oral preparations for the treatment of insomnia, dreaminess, palpitations, shortness of ...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K31/715A61P1/14A61P25/20
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司