Dispersion tablet for treating cardiovascular diseases and its preparation method

A dispersible tablet and cardiovascular technology, which is applied in the field of dispersible tablets for the treatment of cardiovascular diseases and its preparation, can solve the problems of incompatibility of clinical curative effects, and achieve the effects of less adverse reactions, convenient administration, and fast absorption

Inactive Publication Date: 2006-09-06
曹明成
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Problems solved by technology

[0004] In the past ten years, new drugs for the treatment of coronary heart disease and myocardial ischemia have come out continuously, and similar drugs produced by foreign countries or Sino-foreign joint ventures have continuously come to China to seize the beach. ) is still welcomed by many physicians and patients, and proves that it has exuberant vitality, but there is only one kind of Huang Yang Ning tablet, which is not suitable for its remarkable clinical curative effect; Star D), researched and developed "Huangyangning Dispersible Tablet", which has the effects of promoting qi

Method used

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  • Dispersion tablet for treating cardiovascular diseases and its preparation method

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Embodiment Construction

[0024] Examples of the present invention:

[0025] 1. Prescription

[0026] Ringwei Boxwood D 0.5g~3.5g

[0027] Microcrystalline cellulose 20g~40g

[0028] Pregelatinized starch 7g~27g

[0029] Hydroxypropyl cellulose 3g~15g

[0030] Cross-linked povidone 2g~12g

[0031] Aspartame 0.2g~1.2g

[0032] Micronized silica gel 0.02g~0.12g

[0033] Magnesium stearate 0.23g~0.43g

[0034] 2% hypromellose (HPMC) solution Q.S

[0035] 1000 pieces

[0036] 2. Preparation process

[0037] The excipients were dried separately and passed through a 100-mesh sieve; Cyclovirobuxine D (a 200-mesh sieve) was added to the microcrystalline cellulose, pregelatinized starch, hydroxypropyl cellulose, aspartame, Cross-linked povidone and mix well, use 2% HPMC solution to make soft material, granulate through 20-mesh sieve, dry in 60℃ oven, granulate, add finely powdered silica gel and magnesium stearate, mix well, determine content, press tablet , Determine the content, content uniformity, dispersion un...

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Abstract

This invention discloses a disperse tablet for cardiovascular disease therapy and its preparing method. Firstly dry raw materials separately and pass them through 100 orders screen; then adopting equivalent incensement method, mix D with micro-crystal cellulose, gelatinized starch, hydropropyl cellulose, acepaten and crosslinked polyketone, execute it to soft material by 2% hydropropyl methylcellulose, pass the soft material through20 orders screen to produce grains, dry the grains in bake oven at 60deg C, treat the grains, add micronized powder silica gel and stearate, mix, tablet and package is ok. This invention has the characteristics of disintegration rapid, absorption quick, biology availability high, adverse affects few and taking convenient. It has efficacies of promoting Qi and blood, and activate collaterals to relieve pain, it can be used to cure thorax paralysis, heartache and intermittent pulse caused by qi stagnation and blood silt, and coronary disease, arrhythmia with above symptoms. It is especially available to old people and patients difficult to swallow solid.

Description

Technical field [0001] The invention belongs to a new Chinese medicine. More specifically, the invention relates to a dispersible tablet for treating cardiovascular diseases and a preparation method thereof. Background technique [0002] Cardiovascular diseases such as coronary heart disease and myocardial ischemia are one of the most important diseases affecting human health. They have gradually become the leading cause of death among Chinese residents. In addition to the aging population, calling the 21st century "the century of cardiovascular disease" is not Exaggeration, therefore, the development of effective drugs for the prevention and treatment of cardiovascular disease is of great significance for improving the quality of life of patients and extending their lives. [0003] Cardiovascular drugs currently studied are mostly chemical synthetic drugs with large side effects. Huangyangning tablets refined from traditional Chinese medicine prescriptions have significant curat...

Claims

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Application Information

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IPC IPC(8): A61K31/57A61K9/20A61P9/10
Inventor 曹明成
Owner 曹明成
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